Results 141 to 150 of about 22,216 (225)

LSD1 Inhibitor IMG-7289 [PDF]

, 2020
openaire   +1 more source

LSD1 Performs Demethylase-Independent and Context-Specific Roles in Ewing Sarcoma. [PDF]

Cancer Res Commun
Dreher RD, Taslim C, Miller I, Sherman JW, Bayanjargal A, Theisen ER.   +5 more
europepmc   +1 more source

LSD1 promotes prostate cancer cell proliferation by upregulating PRAC1 expression. [PDF]

Sci Rep
Liao Y, Liu C.
europepmc   +1 more source

Discovery of natural apigenin analogues as lysine-specific demethylase 1 inhibitors against tumoral testicular germ cells. [PDF]

Sci Rep
Sun LW, Zhang M, Li CF, Wang C, Li Y.
europepmc   +1 more source

Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation. [PDF]

Signal Transduct Target Ther
Wang J, Wang H, Du R, Li C, Su M, Wang S, Kan W, Liu G, Zhang Y, Hu X, Gao F, Xu G, Li C, Zhu W, Ye Y, Sheng L, Shi Y, Shao Y, Song J, Wang Y, Wang B, Zhou Y, Huang H, Li J, Liu H.   +24 more
europepmc   +1 more source

Reversible and irreversible LSD1 inhibitors

, 2016
Environmental factors and lifestyle can alter the way our genes are expressed influencing a network of chemical switches within our cells collectively known as the Epigenome. Among the epigenetic mechanisms orchestrating the gene expression, methylation is of foremost importance and probably fair to say, still incompletely decoded.
openaire   +1 more source

The novel tertiary amine LSD1 inhibitor 596 inhibits endometrial cancer through the mTOR signal transduction pathway. [PDF]

Transl Oncol
Wang C, Shen D, Lin N, Wang P, Bi Y, Hu H, Shang Y, Ren C, Yang L, Ma Q.   +9 more
europepmc   +1 more source

LSD1 maintains oocyte quality by epigenetically repressing CAMK2β to control granulosa cell-oocyte communication. [PDF]

J Transl Med
Zhang J, Yu Y, Zhu Z, Zhang H, Hu Z, Sheng Z, He M, Zhang T.   +7 more
europepmc   +1 more source

Targeting oral cancer epigenome via LSD1

Aging, 2017
openaire   +2 more sources

Therapeutic advances in acute myeloid leukemia: from LSD1 blockade to PROTAC-based strategies. [PDF]

Ann Med Surg (Lond)
Khan SA, Qamar MA, Feroze MT.
europepmc   +1 more source