Results 31 to 40 of about 6,650,662 (298)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
S.M. Simpson Ltd. -- powerhouse
, 1947 Shift Engineer Lloyd Bohler working at the S.M.
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
S.M. Simpson Ltd. -- tractor on flatbed trailer
, 1940 Logging tractor loaded on a flatbed S.M. Simpson Ltd. truck. In the S.M. Simpson Ltd. mill yard. This type of equipment was introduced around the time that S.M. Simpson Ltd.
core +2 more sources
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Effect of traditional plants in Sri Lanka on skin fibroblast cell number
Data in Brief, 2018 This article describes the effects of extracts of several plants collected in Sri Lanka on the cell number of human skin fibroblasts. This study especially focuses on the plants traditionally used in indigenous systems of medicine in Sri Lanka, such as ...
Katsura Sano +5 more
doaj +1 more source
USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival
Molecular Oncology, EarlyView.CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna +8 more
wiley +1 more source
S.M. Simpson Ltd. -- folding bulk bin prototype
, 1954 Bin prototypes built by S.M. Simpson departing from an idea developed in New Zealand. B.C. Tree Fruits and S.M. Simpson Ltd collaborated as they had a common need to develop a product for use on site in orchards.
core +3 more sources
Hippocampal Long-Term Depression in the Presence of Calcium-Permeable AMPA Receptors
Frontiers in Synaptic Neuroscience, 2018 The GluA2 subunit of AMPA glutamate receptors (AMPARs) has been shown to be critical for the expression of NMDA receptor (NMDAR)-dependent long-term depression (LTD).
Feng Cao +10 more
doaj +1 more source