Results 191 to 200 of about 65,198 (258)

Hazelnut and Walnut Vicilins in Tree Nut Allergy: Co‐Sensitization Patterns and Clinical Severity Associations

Allergy, EarlyView.
This observational analysis of a consecutive tertiary‐care cohort included 70 patients with walnut allergy and 44 patients with hazelnut allergy. Clinical severity was classified as mild, moderate, or severe. Hazelnut and walnut allergy severity was better captured by molecule‐specific IgE profiles than by undifferentiated seed storage protein ...
Danilo Villalta, Giulia Marcassa, Gabriella Cusa, Mariaelisabetta Conte, Francesca Buzzulini, Bo Pontoppidan, Elisabetta Caprini, Jonas Östling, Lars Mattsson, Marie Holmqvist, Mauro Giani, Lorenzo Cecchi, Riccardo Asero, Jonas Lidholm, Enrico Scala   +14 more
wiley   +1 more source

Diagnostic Performance of Recombinant Peanut Allergens in Children: sIgE Cut‐Offs and Anaphylaxis Risk

Acta Paediatrica, EarlyView.
Diagnostic performance of recombinant peanut allergens for anaphylaxis risk in children. (A) Study population and clinical group. (B) Component‐specific IgE cut‐offs and associated odds ratios. (C) Forest plot of odds ratios for anaphylaxis. (D) Clinical interpretation of component‐specific IgE cut‐offs. ABSTRACT Aim Component‐resolved diagnostics (CRD)
Lisa Gazzolari, Annamaria Porreca, Marianna D'Andrea, Claudia Sala, Maurizio Pizzoli, Franca Faraoni, Paola Di Filippo, Dorina Hoxha, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi   +10 more
wiley   +1 more source

Prenatal Stress Induced by Maternal Immune Activation Disrupts GABAergic Inhibition and Mossy Fiber Plasticity in the Rat Dentate Gyrus-CA3 Circuit. [PDF]

Hippocampus
Anguiano-Buenfil J, Sollozo-Dupont I, Márquez LA, Zepeda A, Galván EJ.   +4 more
europepmc   +1 more source

AlpIce‐1: a database of geochronological and geomorphological constraints on Alps‐wide palaeoglacier fluctuations between the Last Glacial Maximum and the Holocene

Boreas, EarlyView.
The AlpIce‐1 database is the first compilation of published geomorphological and geochronological markers constraining build‐up, culmination and decay of glaciers from the Last Glacial Maximum through the Holocene across the entire European Alps. AlpIce‐1 integrates more than 4200 surface‐exposure and radiocarbon ages, homogenized, quality controlled ...
Sarah Kamleitner, Susan Ivy‐Ochs, Tancrède P. M. Leger, Andreas Henz, Samuel U. Nussbaumer, Andreas Vieli, Guillaume Jouvet   +6 more
wiley   +1 more source

Irregular and bursty neuronal firing extend spike-timing dependent plasticity window to behavioral timescales. [PDF]

iScience
Dembitskaya Y, Valtcheva S, Cui Y, Zheng Z, Ostojic S, Graupner M, Venance L.   +6 more
europepmc   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Long-term prophylaxis in hereditary angioedema: Real-world treatment patterns and healthcare resource utilization. [PDF]

World Allergy Organ J
Tachdjian R, Soteres DF, O'Connor M, Maheshwari C, Sehgal A, Wang A, Audhya PK, Craig TJ.   +7 more
europepmc   +1 more source

Adiponectin promotes AMPA receptor trafficking and enhances excitatory synaptic transmission at hippocampal synapses via AMP‐activated protein kinase signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Peripherally derived adiponectin crosses the blood–brain barrier and targets severa0l brain regions. Adiponectin receptors are highly expressed in the hippocampus, and play a pro‐cognitive role as adiponectin markedly influences the functioning of hippocampal synapses.
Alexandra Soca, Patricia Raposo Afonso, Valentin Morfin, James Cantley, Jenni Harvey   +4 more
wiley   +1 more source

Palmitoylation of PSD-95 Orchestrates Learning-Dependent Metaplasticity in the Amygdala and Fear Memory. [PDF]

Adv Sci (Weinh)
Shen ZC, Weng YX, Xia ZX, Zhao YL, Ding QQ, Wang SY, Cao T, Chen XY, Tao WC, Lin S, Chen Z, Luo YX.   +11 more
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source