Optical monitoring of glutamate release at multiple synapses in situ detects changes following LTP induction. [PDF]
Mol Brain, 2020 Information processing and memory formation in the brain relies on release of the main excitatory neurotransmitter glutamate from presynaptic axonal specialisations.
Kopach O, Zheng K, Rusakov DA.
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β-adrenergic signaling broadly contributes to LTP induction. [PDF]
PLoS Comput Biol, 2017 Long-lasting forms of long-term potentiation (LTP) represent one of the major cellular mechanisms underlying learning and memory. One of the fundamental questions in the field of LTP is why different molecules are critical for long-lasting forms of LTP ...
Jȩdrzejewska-Szmek J +3 more
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LTP induction by structural rather than enzymatic functions of CaMKII. [PDF]
Nature, 2023 Learning and memory are thought to require hippocampal long-term potentiation (LTP), and one of the few central dogmas of molecular neuroscience that has stood undisputed for more than three decades is that LTP induction requires enzymatic activity of ...
Tullis JE +10 more
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Acute intracerebral treatment with amyloid-beta (1–42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats [PDF]
Frontiers in Behavioral Neuroscience, 2015 Accumulation of amyloid plaques comprises one of the major hallmarks of Alzheimer’s disease (AD). In rodents, acute treatment with amyloid-beta (Aβ; 1–42) elicits immediate debilitating effects on hippocampal long-term potentiation (LTP).
A. Kalweit +6 more
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Effects of 5-HT3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat [PDF]
Journal of Neuroscience, 1995 Serotonergic brainstem projections to hippocampus are thought to preferentially target and increase, via 5-HT3 receptors, the excitability of a distinct subpopulation of interneurons that primarily regulate GABAB-mediated inhibition in the dendritic ...
U. Staubli, Fangbo Xu
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The effects of kindling during pregnancy on long-term potentiation (LTP) induction and M1 muscarinic acetylcholine receptors in male rat offspring. [PDF]
Res Pharm Sci, 2023 Background and purpose: Neonates of pregnant women with epilepsy may compromise normal neurodevelopment and hippocampal morphology. Memory and learning disorders and a decrease in verbal IQ scores are seen in these children later in life. In the previous
Pourmotabbed A +6 more
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LTP induction modifies functional relationship among hippocampal neurons. [PDF]
Learning & memory (Cold Spring Harbor, N.Y.), 2007 To obtain evidence linking long-term potentiation (LTP) and memory, we examined whether LTP induction modifies functional relationship among neurons in the rat hippocampus.
S. H. Yun +5 more
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Induction of LTP mechanisms in dually innervated dendritic spines [PDF]
Scientific ReportsDendritic spines are the postsynaptic compartments of excitatory synapses, however, a substantial subset of spines additionally receives inhibitory input.
Jonathan E. Tullis, K. Ulrich Bayer
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Exploring new roles for actin upon LTP induction in dendritic spines. [PDF]
Sci Rep, 2021 Bonilla-Quintana M, Wörgötter F.
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LTP Induction Translocates Cortactin at Distant Synapses in Wild-Type But Not Fmr1 Knock-Out Mice [PDF]
Journal of Neuroscience, 2012 Stabilization of long-term potentiation (LTP) depends on reorganization of the dendritic spine actin cytoskeleton. The present study tested whether this involves activity-driven effects on the actin-regulatory protein cortactin, and whether such effects ...
R. Seese +6 more
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