Voluntary running improves synaptic degeneration of the anterior cingulate cortex in knee osteoarthritis. [PDF]
Miyake R +8 more
europepmc +1 more source
This systematic review emphasizes the critical role of GABAB receptors (GABABR) in alcohol use disorder (AUD). While GABABR agonists enhance cortical inhibition, as measured by transcranial magnetic stimulation (TMS)‐based markers, alcohol consumption alters GABABR ‐dependent neurophysiological measures, suggesting GABABR dysfunction plays a key role ...
Chiara Montemitro +4 more
wiley +1 more source
Synapse-specific compartmentalization of signaling cascades for LTP induction in CA3 interneurons. [PDF]
Galván EJ +5 more
europepmc +1 more source
Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz +3 more
wiley +1 more source
Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices. [PDF]
Wang A +7 more
europepmc +1 more source
Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen +12 more
wiley +1 more source
Social memory engram formation impairment in neuroligin-3 R451C knock-in mice is caused by disrupted prefrontal NMDA receptor-dependent potentiation. [PDF]
Li Z +14 more
europepmc +1 more source
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Long-term potentiation and long-term depression are both impaired after<i>in vitro</i>stretch injury measured with stretchable microelectrode arrays. [PDF]
Dwyer MKR +4 more
europepmc +1 more source

