Results 241 to 250 of about 22,985 (275)

cAMP reduces action potential amplitude and conduction velocity over long axonal distance

open access: yes
The Journal of Physiology, EarlyView.
Fabrice Abate   +2 more
wiley   +1 more source

A developmental switch in the signaling cascades for LTP induction [PDF]

open access: possibleNature Neuroscience, 2002
Long-term potentiation (LTP) is thought to be critically involved not only in learning and memory, but also during the activity-dependent developmental phases of neural circuit formation and refinement. Whether the mechanisms underlying LTP change during this phase of postnatal development, however, is unknown.
Alison L. Barth   +3 more
openaire   +2 more sources

GABAB autoreceptors regulate the induction of LTP

Nature, 1991
Understanding the mechanisms involved in long-term potentiation (LTP) should provide insights into the cellular and molecular basis of learning and memory in vertebrates. It has been established that in the CA1 region of the hippocampus the induction of LTP requires the transient activation of the N-methyl-D-aspartate (NMDA) receptor system. During low-
Graham L. Collingridge   +7 more
openaire   +3 more sources

Endocannabinoids facilitate the induction of LTP in the hippocampus

Nature Neuroscience, 2002
Exogenous cannabinoids disrupt behavioral learning and impede induction of long-term potentiation (LTP) in the hippocampus, yet endogenous cannabinoids (endocannabinoids) transiently suppress inhibitory post-synaptic currents (IPSCs) by activating cannabinoid CB1 receptors on GABAergic interneurons.
Gregory C. Carlson   +2 more
openaire   +3 more sources

Coactivation of metabotropic and NMDA receptors is required for LTP induction

NeuroReport, 1993
Induction of long-term potentiation (LTP) of synaptic transmission in the CA1 region of the hippocampus is dependent on N-methyl-D-aspartate (NMDA) receptor activation. However, NMDA receptor stimulation alone is not adequate to trigger LTP. Results from the present study indicate that, in addition to NMDA receptors, there is a requirement for co ...
Barbara A. Ballyk   +2 more
openaire   +3 more sources

Evidence that matrix recognition contributes to stabilization but not induction of LTP

NeuroReport, 1991
Slices of hippocampus were incubated with Arg-Gly-Asp (RGD) peptides known to block members of the integrin class of matrix receptors. Though the peptides caused no detectable difference in the amount of long-term potentiation (LTP) expressed in the CA1 field 1-2 min after induction with high frequency stimulation, they did produce a reversible, dose ...
Ben A. Bahr   +4 more
openaire   +3 more sources

Nicotine primes the effect of cocaine on the induction of LTP in the amygdala

Neuropharmacology, 2013
In human populations, there is a well-defined sequence of involvement in drugs of abuse, in which the use of nicotine or alcohol precedes the use of marijuana, which in turn, precedes the use of cocaine. The term "Gateway Hypothesis" describes this developmental sequence of drug involvement.
Amir Levine   +3 more
openaire   +2 more sources

Induction of LTP in the human auditory cortex by sensory stimulation

European Journal of Neuroscience, 2005
AbstractHigh‐frequency, repetitive, auditory stimulation was used to determine whether induction of a long‐lasting increase of the human auditory evoked potential (AEP) was possible. Recording non‐invasively with electroencephalogram scalp electrodes, stable increases in amplitude were observed in the N1 component of the AEP, which is thought to ...
Daniel Shepherd   +4 more
openaire   +3 more sources

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