In silico investigation of the puzzling dopamine effects on excitability and synaptic plasticity in hippocampal CA1 pyramidal neurons. [PDF]
Manara E, Mele A, Migliore M.
europepmc +1 more source
Abstract Cupuassu (Theobroma grandiflorum) is a fruit tree native to the Brazilian Amazon and increasingly relevant to regional bioeconomies. Its cultivation is severely affected by witches’ broom disease (WBD), caused by Moniliophthora perniciosa. While a chromosome‐scale genome of the susceptible genotype C1074 is available, the lack of a resistant ...
Vinicius A. C. de Abreu +8 more
wiley +1 more source
From Synaptic Plasticity and Critical Periods to Social Behavior and Stress: Getting to, and Staying in, CA2. [PDF]
Dudek SM.
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Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen +12 more
wiley +1 more source
D-Serine's Journey Between Stars and Synapses. [PDF]
Mountadem S, Oliet SHR, Panatier A.
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Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
MiR-33-5p-opioidergic Signaling Regulates Cognitive Impairment Induced by Bile Duct Ligation in Rats: Ameliorative Role of Naloxone. [PDF]
Rahimi-Vala M +4 more
europepmc +1 more source
This study demonstrated single‐crystalline PbTiO3‐based memristors with atomically sharp interfaces, well‐ordered lattices, and minimal lattice mismatch. The devices exhibited an ON/OFF ratio exceeding 105, high stability, and rich resistance‐state modulation.
Haining Li +7 more
wiley +1 more source
Alpha-Ketoglutarate Ameliorates Synaptic Plasticity Deficits in APP/PS1 Mice Model of Alzheimer's Disease. [PDF]
Navakkode S, Kennedy BK.
europepmc +1 more source
Immediate early genes expression in the cerebellar cortex correlates with LTP and LTD induction
Mariarosa Polimeni +9 more
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