Results 291 to 300 of about 47,591 (317)
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Science's STKE, 2006
Although neuron-glia crosstalk has been studied extensively in the past, it has not been clear that the signaling mediating this crosstalk exhibits any activity-dependent plasticity, such as the phenomenon of long-term potentiation (LTP) that is thought to represent the electrophysiological representation of memory. Ge et al.
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Although neuron-glia crosstalk has been studied extensively in the past, it has not been clear that the signaling mediating this crosstalk exhibits any activity-dependent plasticity, such as the phenomenon of long-term potentiation (LTP) that is thought to represent the electrophysiological representation of memory. Ge et al.
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Induction of LTP in rat primary visual cortex: tetanus parameters
Brain Research, 1989Long-term potentiation (LTP), intensively studied in the hippocampus as a possible mnemonic device, has begun to be studied in the neocortex. In this study the effects of varying tetanic stimulus parameters on LTP of field potentials recorded from layer II/III induced by white matter stimulation in the in vitro rat visual cortical slice were examined ...
R L, Berry, T J, Teyler, T Z, Han
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Dendritic Spine Density and LTP Induction in Cultured Hippocampal Slices
Journal of Neurophysiology, 1997Collin, Carlos, Katsuyuki Miyaguchi, and Menahem Segal.Dendritic spine density and LTP induction in cultured hippocampal slices. J. Neurophysiol. 77: 1614–1623, 1997. Transverse hippocampal slices were cut from 8- to 9-day-old rats and maintained in an interface chamber for periods of 1–4 wk, in tissue culture conditions.
C, Collin, K, Miyaguchi, M, Segal
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A developmental switch in the signaling cascades for LTP induction
Nature Neuroscience, 2002Long-term potentiation (LTP) is thought to be critically involved not only in learning and memory, but also during the activity-dependent developmental phases of neural circuit formation and refinement. Whether the mechanisms underlying LTP change during this phase of postnatal development, however, is unknown.
Hiroki, Yasuda +3 more
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Presynaptic induction and expression of NMDA-dependent LTP
Trends in Neurosciences, 2004It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potentiation (LTP) is a cellular substrate of memory. As a result, memory impairments caused by experimental reductions of NMDA currents are often interpreted as evidence that this form of plasticity is involved in memory formation.
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Dopamine gates LTP induction in lateral amygdala by suppressing feedforward inhibition
Nature Neuroscience, 2003Fear conditioning involves the induction of long-term potentiation (LTP) of excitatory synaptic transmission in the lateral amygdala, a brain structure which is tightly controlled by GABAergic inhibition. Here we show that dopamine gates the induction of LTP in the mouse lateral amygdala by suppressing feedforward inhibition from local interneurons ...
Stephanie, Bissière +2 more
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Journal of Neurophysiology, 2021
The induction of LTP in the hippocampus was bidirectionally regulated by prior postsynaptic cell firing, with θ-burst stimulation-induced LTP being consistently impaired by prior spiking, whereas high-frequency stimulation-induced LTP was either not changed or facilitated.
Regina U, Hegemann, Wickliffe C, Abraham
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The induction of LTP in the hippocampus was bidirectionally regulated by prior postsynaptic cell firing, with θ-burst stimulation-induced LTP being consistently impaired by prior spiking, whereas high-frequency stimulation-induced LTP was either not changed or facilitated.
Regina U, Hegemann, Wickliffe C, Abraham
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Acute and chronic nicotine exposure differentially facilitate the induction of LTP
Brain Research, 1999We report here that acute and chronic nicotine exposure facilitated the induction of long-term potentiation (LTP), a leading candidate for a cellular mechanism underlying learning and memory, in the hippocampus. Furthermore, acute application of nicotine in chronic nicotine-treated hippocampus further facilitated the induction of LTP, suggesting that ...
S, Fujii, Z, Ji, N, Morita, K, Sumikawa
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Neural Networks, 2011
Synaptic plasticity leads to long-term changes in excitability, whereas cellular homeostasis maintains excitability. Both these processes involve interactions between molecular events, electrical events, and network activity. Here I explore these intersections with a multilevel model that embeds molecular events following synaptic calcium influx into a
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Synaptic plasticity leads to long-term changes in excitability, whereas cellular homeostasis maintains excitability. Both these processes involve interactions between molecular events, electrical events, and network activity. Here I explore these intersections with a multilevel model that embeds molecular events following synaptic calcium influx into a
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Coactivation of metabotropic and NMDA receptors is required for LTP induction
NeuroReport, 1993Induction of long-term potentiation (LTP) of synaptic transmission in the CA1 region of the hippocampus is dependent on N-methyl-D-aspartate (NMDA) receptor activation. However, NMDA receptor stimulation alone is not adequate to trigger LTP. Results from the present study indicate that, in addition to NMDA receptors, there is a requirement for co ...
M A, Musgrave, B A, Ballyk, J W, Goh
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