Results 51 to 60 of about 1,151,700 (338)
PLoS ONE, 2013 NMDA receptor subunits change during development and their synaptic expression is modified rapidly after synaptic plasticity induction in hippocampal slices.
M. V. Baez +5 more
semanticscholar +1 more source
Synaptic tagging and capture : differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation [PDF]
, 2010 Weakly tetanized synapses in area CA1 of the hippocampus that ordinarily display long-term potentiation lasting ~3 h (called early-LTP) will maintain a longer-lasting change in efficacy (late-LTP) if the weak tetanization occurs shortly before or after ...
Bito, Haruhiko +5 more
core +2 more sources
Postsynaptic Induction and PKA-Dependent Expression of LTP in the Lateral Amygdala [PDF]
Neuron, 1998 Whereas much is now known about the behavioral importance of the lateral nucleus of the amygdala for the storage of implicit memories of fear, little is known in molecular terms about the signal transduction pathways required for long-term potentiation (LTP) in this nucleus. Using brain slices containing the amygdala, we have studied LTP in the pathway
Yan-You Huang, Eric R. Kandel
openaire +3 more sources
Interactions between short-term and long-term plasticity: shooting for a moving target [PDF]
, 2011 Far from being static transmission units, synapses are highly dynamical elements that change over multiple time scales depending on the history of the neural activity of both the pre- and postsynaptic neuron.
Jean-Pascal Pfister, Má
core +2 more sources
What does LTP tell us about the roles of CaMKII and PKMζ in memory?
Molecular Brain, 2018 In “Criteria for identifying the molecular basis of the engram (CaMKII, PKMζ),” Lisman proposes that elucidating the mechanism of LTP maintenance is key to understanding memory storage.
Todd Charlton Sacktor +1 more
doaj +1 more source
iScience, 2023 Summary: The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is crucial for translation and regulated by Ser209 phosphorylation. However, the biochemical and physiological role of eIF4E phosphorylation in translational control of long ...
Sudarshan Patil +7 more
doaj +1 more source
State based model of long-term potentiation and synaptic tagging and capture [PDF]
, 2009 Recent data indicate that plasticity protocols have not only synapse-specific but also more widespread effects. In particular, in synaptic tagging and capture (STC), tagged synapses can capture plasticity-related proteins, synthesized in response to ...
A Govindarajan +50 more
core +4 more sources
Molecular Brain, 2010 Neurogenesis occurs in the adult hippocampus of various animal species. A substantial fraction of newly generated neurons die before they mature, and the survival rate of new neurons are regulated in an experience-dependent manner.
T. Kitamura +4 more
semanticscholar +1 more source
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy
Molecular Pain, 2011 Long-term potentiation (LTP) in nociceptive spinal pathways shares several features with hyperalgesia and has been proposed to be a cellular mechanism of pain amplification in acute and chronic pain states.
Liu Xian-Guo +4 more
doaj +1 more source
Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model. [PDF]
PLoS Computational Biology, 2012 Protein synthesis-dependent, late long-term potentiation (LTP) and depression (LTD) at glutamatergic hippocampal synapses are well characterized examples of long-term synaptic plasticity.
Paul Smolen +2 more
doaj +1 more source