Results 61 to 70 of about 1,151,700 (338)

Requirement of extracellular signal-regulated kinase/mitogen-activated protein kinase for long-term potentiation in adult mouse anterior cingulate cortex

Molecular Pain, 2007
Long-term potentiation (LTP) in the anterior cingulate cortex (ACC) is believed to be critical for higher brain functions including emotion, learning, memory and chronic pain.
Ren Ming, Wu Long-Jun, Xu Hui, Zhao Ming-Gao, Toyoda Hiroki, Zhuo Min   +5 more
doaj   +1 more source

Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus [PDF]

, 1997
Autophosphorylation of calcium/calmodulin-dependent protein kinase II (CaMKII) at threonine-286 produces Ca2+-independent kinase activity and has been proposed to be involved in induction of long-term potentiation by tetanic stimulation in the ...
Harris, Kristen M., Kantor, David, Kennedy, Mary B., Ouyang, Yannan, Schuman, Erin M.   +4 more
core   +2 more sources

Physiological effects of enriched environment exposure and LTP induction in the hippocampus in vivo do not transfer faithfully to in vitro slices.

Learning & memory (Cold Spring Harbor, N.Y.), 2010
A number of experimental paradigms use in vitro brain slices to test for changes in synaptic transmission and plasticity following a behavioral manipulation.
M. Eckert, W. Abraham
semanticscholar   +1 more source

Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus. [PDF]

PLoS ONE, 2012
Activation of muscarinic acetylcholine receptors (mAChR) facilitates the induction of synaptic plasticity and enhances cognitive function. In the hippocampus, M(1) mAChR on CA1 pyramidal cells inhibit both small conductance Ca(2+)-activated KCa2 ...
Milos M Petrovic, Jakub Nowacki, Valeria Olivo, Krasimira Tsaneva-Atanasova, Andrew D Randall, Jack R Mellor   +5 more
doaj   +1 more source

Long-Term Potentiation: One Kind or Many? [PDF]

, 2016
Do neurobiologists aim to discover natural kinds? I address this question in this chapter via a critical analysis of classification practices operative across the 43-year history of research on long-term potentiation (LTP).
A Dolphin, AM Watabe, B Alger, C Craver, C Craver, C Craver, C Craver, C Craver, C Craver, C Craver, C Stinson, D Hebb, E Harris, E Kandel, E Kandel, G Lynch, G Lynch, G Piccinini, J Bickle, J Bogen, J Lisman, J Sullivan, J Woodward, JD English, JD English, JD Sweatt, JD Sweatt, K Kendler, M Baudry, M Baudry, M Bennett, M Browning, P Anderson, P Machamer, R Douglas, R Malenka, R Malenka, R Malenka, R Nicoll, R Nicoll, S Deadwyler, T Bliss, T Bliss, T Dunwiddie, T Lomo, U Feest, U Staubli, W Bechtel, W Bechtel, W Bechtel, W Wimsatt   +50 more
core   +3 more sources

Nitric oxide and synaptic function [PDF]

, 1994
The free radical gas nitric oxide (NO) is a recently identified neuronal messenger that carries out diverse signaling tasks in both the central and peripheral nervous systems.
Madison, Daniel V., Schuman, Erin M.
core   +1 more source

Genetic Dissection of Presynaptic and Postsynaptic BDNF-TrkB Signaling in Synaptic Efficacy of CA3-CA1 Synapses

Cell Reports, 2018
Summary: Brain-derived neurotrophic factor (BDNF) and its high-affinity receptor, tropomyosin receptor kinase B (TrkB), regulate long-term potentiation (LTP) in the hippocampus, although the sites of BDNF-TrkB receptors in this process are controversial.
Pei-Yi Lin, Ege T. Kavalali, Lisa M. Monteggia   +2 more
doaj   +1 more source

The CaMKII/NMDAR complex as a molecular memory

Molecular Brain, 2013
CaMKII is a major synaptic protein that is activated during the induction of long-term potentiation (LTP) by the Ca2+ influx through NMDARs. This activation is required for LTP induction, but the role of the kinase in the maintenance of LTP is less clear.
Sanhueza Magdalena, Lisman John
doaj   +1 more source

The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms. [PDF]

, 2018
CaMKII is one of the most studied synaptic proteins, but many critical issues regarding its role in synaptic function remain unresolved. Using a CRISPR-based system to delete CaMKII and replace it with mutated forms in single neurons, we have rigorously ...
Asensio, Cedric S, Bender, Kevin J, Díaz-Alonso, Javier, Iafrati, Jillian, Incontro, Salvatore, Nicoll, Roger A, Roche, Katherine W, Sohal, Vikaas S, Vieira, Marta   +8 more
core   +2 more sources

A Mathematical model for Astrocytes mediated LTP at Single Hippocampal Synapses

, 2012
Many contemporary studies have shown that astrocytes play a significant role in modulating both short and long form of synaptic plasticity. There are very few experimental models which elucidate the role of astrocyte over Long-term Potentiation (LTP ...
A Araque, A Destexhe, AG Nikonenko, AL Hodgkin, AM Weber, AM Zhabotinsky, B Katz, B Mouillac, B Sahin, BL Bloodgood, BL Sabatini, BL Sabatini, C Agulhon, C Agulhon, C Fall, C Henneberger, C Koch, CLM Bon, D Dumitriu, D Sochivko, DJ Hagler Jr, DX Keller, E Neher, EB Malarkey, ER Higgins, F Erler, F Helmchen, F Taqatqeh, G Perea, GA Rameau, GL Collingridge, GW Young De, H-K Lee, HJ Koester, HV McCue, I Nikonenko, I Wenker, J Bai, J Boehm, J Garthwaite, J Kang, J Keener, J Lisman, J Marchaland, J Sneyd, J-W Shuai, JA Bibb, JE Lisman, JH Bollmann, JH Bollmann, JT Porter, Kaushik Majumdar, KD Micheva, KG Phillips, KM Franks, KT Blackwell, L-C Ching, L-Y Wang, LC Griffith, M Mazzanti, M Pittà De, M Tsodyks, MS Jafri, N Aslam, NC Danbolt, NJ Emptage, P Bezzi, P Miller, PP Atluri, R Anwyl, R Bertram, R Llinas, R Schneggenburger, R Schneggenburger, R Vargas, RA Hopper, RC Malenka, RF Fox, RP Munton, S Ben Achour, S Nadkarni, S Nadkarni, Shivendra Tewari, SJ Taylor, T Ishikawa, TA Fiacco, TP Jensen, TVP Bliss, TVP Bliss, V Calabrese, V Montana, V Parpura, V Parpura, V Volman, WT Coffey, Y Watanabe, Y-X Li, Z Nusser   +97 more
core   +1 more source