Results 71 to 80 of about 1,151,700 (338)

Intracellular mechanisms underlying the nicotinic enhancement of LTP in the rat dentate gyrus [PDF]

open access: yes, 2008
We have previously shown that activation of nicotinic acetylcholine receptors (nAChRs) enhanced long-term potentiation (LTP) in the rat dentate gyrus in vitro via activation of α7 nAChR. In the present studies, mechanisms underlying the acute and chronic
Abel   +81 more
core   +1 more source

Temporal profiling of gene networks associated with the late phase of long-term potentiation in vivo.

open access: yesPLoS ONE, 2012
Long-term potentiation (LTP) is widely accepted as a cellular mechanism underlying memory processes. It is well established that LTP persistence is strongly dependent on activation of constitutive and inducible transcription factors, but there is limited
Margaret M Ryan   +6 more
doaj   +1 more source

Modeling Maintenance of Long-Term Potentiation in Clustered Synapses, Long-Term Memory Without Bistability [PDF]

open access: yes, 2015
Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist?
Smolen, Paul
core   +4 more sources

Orexin and cannabinoid systems modulate long-term potentiation of the hippocampus CA1 area in anesthetized rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Long-term potentiation (LTP) is a kind of synaptic plasticity and has a key role in learning and memory. Endocannabinoids and orexins are the endogenous systems that can modulate synaptic plasticity.
Reza Fartootzadeh   +3 more
doaj   +1 more source

Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]

open access: yes, 2017
The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica   +9 more
core   +2 more sources

Opioid receptor activation is one factor underlying the frequency dependence of mossy fiber LTP induction

open access: yesJournal of Neuroscience, 1994
The contribution of high-frequency synaptic activity to the induction of long-term potentiation (LTP) in the opioid peptide-containing mossy fiber projection was investigated in vivo in anesthetized rats.
B. Derrick, Jl Martinez
semanticscholar   +1 more source

Ventral tegmental area inactivation suppresses the expression of CA1 long term potentiation in anesthetized rat.

open access: yesPLoS ONE, 2013
The hippocampus receives dopaminergic projections from the ventral tegmental area (VTA). Modulatory effect of dopamine on hippocampal long term potentiation (LTP) has been studied before, but there are conflicting results and some limitations in previous
Elham Ghanbarian, Fereshteh Motamedi
doaj   +1 more source

Mimicking Synaptic Plasticity: Optoionic MoS2 Memory Powered by Biopolymer Hydrogels as a Dynamic Cations Reservoir

open access: yesAdvanced Functional Materials, EarlyView.
Janus (MoS2) transistors functionalized with sodium alginate (SA) and poly(vinylidene fluoride‐co‐trifluoroethylene) [P(VDF‐TrFE)] exhibit persistent photo‐induced ionic gating, driven by dynamic cation migration at the hybrid interface. This ionic mechanism enables finely tunable photoconductivity and emulates key synaptic plasticity behaviors ...
Yeonsu Jeong   +5 more
wiley   +1 more source

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]

open access: yes, 2014
Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J   +2 more
core   +1 more source

Mechanisms and Role of Dendritic Membrane Trafficking for Long-Term Potentiation

open access: yesFrontiers in Cellular Neuroscience, 2018
Long-term potentiation (LTP) of excitatory synapses is a major form of plasticity for learning and memory in the central nervous system. While the molecular mechanisms of LTP have been debated for decades, there is consensus that LTP induction activates ...
Brian G. Hiester   +4 more
doaj   +1 more source

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