Results 61 to 70 of about 1,035,856 (262)

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control

open access: yesAdvanced Science, EarlyView.
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias   +23 more
wiley   +1 more source

Atomistic Kinetics of Dislocation‐Mediated Grain Growth in Monolayer MoS2

open access: yesAdvanced Science, EarlyView.
Atomic‐resolution in‐situ heating microscopy directly visualizes dislocation‐mediated grain boundary migration and grain growth in monolayer MoS2. Mobile grain boundaries migrate through collective motion of Mo 5|7 dislocations, whereas S 5|7 defects remain largely immobile.
Chang‐Won Choi   +11 more
wiley   +1 more source

Phase diagrams for the M2MoO4–Ln2(MoO4)3–Hf(MoO4)2 systems, where M = Li–Cs, Tl and Ln = La–Lu

open access: yesChimica Techno Acta, 2017
In this paper, the results of systematic studies of complex molybdate systems M2MoO4–Ln2(MoO4)3–Hf(MoO4)2 (M = Li–Cs, Tl; Ln = La–Lu) are presented. Subsolidus phase diagrams of ternary systems were constructed and new triple molybdates were obtained ...
Zh. G. Bazarova   +5 more
doaj   +1 more source

Half-life of the nuclear cosmochronometer 176Lu measured with a windowless 4π solid angle scintillation detector

open access: yesCommunications Physics, 2023
The 176Lu-176Hf nuclear decay is a powerful tool to measure the age of astrophysical and geological events and has been used as a “cosmochronometer”.
Takehito Hayakawa   +2 more
doaj   +1 more source

Lu–Hf isotope systematics of fossil biogenic apatite and their effects on geochronology

open access: yesGeochimica et Cosmochimica Acta, 2013
Abstract Reliable methods for direct dating of biogenic apatite from pre-Pleistocene fossils are currently not available, and recent attempts using the Lu–Hf decay system yielded highly inaccurate ages for both bones and teeth. The geological processes accounting for this poor accuracy of Lu–Hf chronometry are not yet understood.
Herwartz, Daniel   +5 more
openaire   +2 more sources

Multi‐Modal Low‐Power Adaptive Braille Recognition System Based on Hf0.3Zr0.7O2 Memristor

open access: yesAdvanced Science, EarlyView.
A multimodal adaptive perception system based on HZO ferroelectric memristor realizes efficient Braille digit recognition via reservoir computing. It delivers high recognition accuracy with ultralow‑energy analog computation, offering a promising hardware solution for environment‑robust neuromorphic assistive devices for visually impaired users ...
Jikang Xu   +9 more
wiley   +1 more source

Feasibility of blood self-sampling with HemaSpot HF for Anti-Clostridium tetani Toxin IgG detection

open access: yesScientific Reports
Health research in humans often requires biosamples, e.g. blood. However, collecting venous blood samples poses multiple logistic challenges and needs to be carried by practitioners at study centres.
R. Kettlitz   +4 more
doaj   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

open access: yesAdvanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen   +5 more
wiley   +1 more source

LU-HF Age and Isotope Systematics of ALH84001 [PDF]

open access: yes, 2009
Allan Hills (ALH) 84001 is an orthopyroxenite that is unique among the Martian meteorites in having the oldest inferred crystallization age (approx..4.5 to 4.0 Gyr) [e.g., 1-6 and references therein 7].
Righter, M.   +5 more
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