Results 71 to 80 of about 1,035,856 (262)

Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution

open access: yesAdvanced Science, EarlyView.
MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge   +6 more
wiley   +1 more source

Temporal and Hf isotope geochemical evolution of southern Finnish Lapland from 2.77 Ga to 1.76 Ga [PDF]

open access: yesBulletin of the Geological Society of Finland, 2012
The southern Finnish Lapland area in the central part of the Fennoscandian shield is a geologically complex zone comprising several Archean blocks and Paleoproterozoic supracrustal belts all of which are intruded by voluminous Paleoproterozoic granites ...
L.S. Lauri   +3 more
doaj   +1 more source

Dual Compartmentalization of GSTA4 Suppresses Ferroptosis to Drive Antiandrogen Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
The schematic diagram depicts a compartmentalized anti‐ferroptotic defense mechanism mediated by GSTA4. GSTA4 is upregulated and localizes to the cytoplasm in ENZR cells, where it detoxifies 4‐HNE via a non‐canonical GSH‐dependent pathway. Under oxidative stress, GSTA4 translocates to mitochondria, interacts with PGAM5, and blocks Drp1 Ser637 ...
Yong Luo   +17 more
wiley   +1 more source

Zircon U–Pb Dating and Lu-Hf Isotope of the Retrograded Eclogite from Chicheng, Northern Hebei Province, China

open access: yesShock and Vibration, 2021
We report zircon U–Pb ages and Lu-Hf isotopic data from two sample of the retrograded eclogite in the Chicheng area. Two groups of the metamorphic zircons from the Chicheng retrograded eclogite were identified: group one shows characteristics of ...
Xu Kong   +3 more
doaj   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

open access: yesAdvanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang   +4 more
wiley   +1 more source

Array‐Level Characterization of Cryogenic RRAM

open access: yesAdvanced Electronic Materials, EarlyView.
This paper reports the first array‐level comprehensive electrical characterization of a 1024‐device HfO2‐based RRAM array from 300, 77 to 4 K, covering forming, set/reset switching, endurance, retention, relaxation, and read disturb. The results manifest the high performance of RRAM array at cryogenic temperatures and huge application potential for ...
Yuyao Lu   +7 more
wiley   +1 more source

Surface modification effect on the repair bond strength of hybrid and non-hybrid ceramics

open access: yesBMC Oral Health
Background This study investigated the appropriate surface treatment protocols for repairing various hybrid and non-hybrid ceramics. Methods Ceramic samples with a thickness of 2 mm were prepared from two resin-hybrid CAD/CAM blocks (Vita Enamic (hybrid ...
Naeeme Naderi   +4 more
doaj   +1 more source

On the relationship between the velocity of E-region HF echoes and E B plasma drift [PDF]

open access: yes, 2005
International audienceIn this study, velocities of E-region HF echoes observed by the Stokkseyri HF radar are compared with ExB plasma drifts in the F-region measured by the DMSP satellites.
D. W. Danskin   +7 more
core   +2 more sources

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

open access: yesAdvanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku   +5 more
wiley   +1 more source

Lu–Hf Isotope Systematics of Carbonatites [PDF]

open access: yesGoldschmidt Abstracts, 2020
Ladislav Polák   +4 more
openaire   +1 more source

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