Results 201 to 210 of about 44,149 (263)

Heparanase‐Loaded CAR T Extracellular Vesicles Remodel the Colorectal Tumour Microenvironment and Boost T Cell Antitumor Immunity

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Dense ECM restricts CAR T efficacy in solid tumours. Zhu et al. design mesothelin‐targeted CAR T cells that secrete heparanase‐rich extracellular vesicles via a truncated hepatitis A virus pX domain (pX‐Δ1‐30), promoting ECM degradation, durable memory, and less exhausted phenotypes, leading to strong antitumor responses in colorectal cancer spheroids ...
Songshan Zhu, Jun Yin, Weiqiang Yang, Xin Fu, Yiwei Zeng, Na Huang, Ling Zhang, Cong Yu, Ping Ouyang, Kaisong Huang, Rui Chen, Xiaolei Zhao, Dan Jiang, Guangxian Xu   +13 more
wiley   +1 more source

An advanced multimodal image fusion model for accurate detection of Alzheimer's disease using MRI and PET. [PDF]

Front Med Technol
Ansari AS, Mohammadi MS, Cattani C, Tassaddiq A.   +3 more
europepmc   +1 more source

<i>Chaetopterus</i> Luciferase: A Promising Tool for Online Lipid Peroxidation Detection. [PDF]

Int J Mol Sci
Shcheglov AS, Purtov KV, Zagitova RI, Kozhemyako VB, Tsarkova AS, Pepoyan A, Yampolsky IV.   +6 more
europepmc   +1 more source

Longitudinal Analysis of Male Fertility Using an Acr-Luc Knock-In Mouse Model: A Preclinical Platform for Reproductive Toxicity Testing. [PDF]

MedComm (2020)
Fukunaga H, Seino R, Matsuya Y, Takashima H, Ishikawa M, Onodera Y, Shirato H, Miyata H, Prise KM.   +8 more
europepmc   +1 more source

A step towards animal models with self-sustained fungal bioluminescence

Gleneadie HJ, Veland N, Warren EC, Sardini A, Barroso C, Fadeeva AA, Webster Z, Dormann D, Gao F, Martinez-Perez E, Merkenschlager M, Sarkisyan K, Fisher AG.   +12 more
europepmc   +1 more source

Red-shifted d-luciferin analogues and their bioluminescence characteristics. [PDF]

RSC Chem Biol
Watthaisong P, Kantiwiriyawanitch C, Jitkaroon W, Phintha A, Klayparn I, Lawan N, Kamutira P, Sasaki D, Visitsatthawong S, Maenpuen S, Tinikul R, Sucharitakul J, Nishihara R, Niwa K, Nakajima Y, Ohmiya Y, Chaiyen P.   +16 more
europepmc   +1 more source

[Synthesis of Cypridina luciferin and related compounds. 3. Synthesis of cypridina luciferin].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1970
Y, Kishi, S, Sugiura, S, Inoue, T, Goto
openaire   +1 more source

New insights for an old drug: difluoromethylornithine boosts the trypanocidal action of benznidazole on <i>Trypanosoma cruzi in vitro</i> and <i>in vivo</i>. [PDF]

Front Cell Infect Microbiol
Martínez SJ, Vanrell MC, Li X, Carrillo C, Engman DM, Romano PS.   +5 more
europepmc   +1 more source

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Induction of bioluminescence in a luciferin deficient form of the marine teleost, Porichthys, in response to exogenous luciferin

Comparative Biochemistry and Physiology A, Comparative Physiology, 1973
Abstract 1. 1. The inability of Porichthys from Puget Sound to luminesce is correlated with a luciferin deficiency in all developmental stages. 2. 2. Luminescence capability can be induced in non-luminous Porichthys by intraperitoneal injection or forced feeding with luciferin from either Cypridina or luminous Porichthys . 3.
F I Tsuji, James F Case
exaly   +3 more sources