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Lumacaftor/Ivacaftor: A Review in Cystic Fibrosis
Drugs, 2016Lumacaftor/ivacaftor (Orkambi™) is a fixed-dose tablet containing a corrector (lumacaftor) and potentiator (ivacaftor) of the cystic fibrosis transmembrane conductance regulator (CFTR) and is the first therapy approved to treat the underlying cause of cystic fibrosis in patients (aged ≥12 years) homozygous for the most common CFTR mutation, F508del ...
openaire +2 more sources
Real-Life Safety and Effectiveness of Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis
American Journal of Respiratory and Critical Care Medicine, 2020Dominique Hubert +2 more
exaly
Adherence to lumacaftor-ivacaftor therapy in patients with cystic fibrosis in France
Journal of Cystic Fibrosis, 2020Stephan Garcia
exaly

