Results 51 to 60 of about 44,115 (283)

Social Determinants of Spinal Pathology in Adolescents From Urban Centers in the Post‐Medieval Netherlands (1650–1850 CE)

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The study of trauma in individuals undergoing growth and development remains an understudied area of research but can provide unique insights into the lived experiences and social identities of young people in the past. This study examines vertebral compression fractures and Schmorl's nodes in children and adolescents (1–20 years at death ...
Meghan D. Langlois, Rachel Schats, Sarah Burrow, Megan B. Brickley   +3 more
wiley   +1 more source

The Extraforaminal Approach for the Management of Far Lateral Lumbar Disc Herniation

Egyptian Spine Journal, 2017
Background Data: Far lateral lumbar disc herniation accounts for 1-12% of all lumbar disc herniations. Every aspect of management of this unique type of lumbar disc herniation is challenging for spine surgeons, and no consensus has been reached for the ...
Al Moataz El-Sabrout, Mohammad El-Sharkawi, Mohamed El-Meshtawy, Romany Zaki   +3 more
doaj   +1 more source

Chiropractic spinal manipulative therapy versus physical therapist‐led exercise and the risk of cauda equina syndrome in adults with lumbar disc herniation, stenosis, or radiculopathy

PM&R, EarlyView.
Abstract Background Cauda equina syndrome is a surgical emergency often caused by lumbar disc herniation. Spinal manipulative therapy is commonly used for lumbar spine disorders, but case reports have raised concerns it may precipitate cauda equina syndrome. One cohort study suggested no increased risk, although it did not focus on patients with lumbar
Robert J. Trager, Anthony N. Baumann, Romeo‐Paolo T. Perfecto, Christine M. Goertz   +3 more
wiley   +1 more source

Effect of transcutaneous electrical nerve stimulation on physical activity and pain evaluation in osteoarthritic dogs

Veterinary Record, EarlyView.
Abstract Background Osteoarthritis (OA) causes chronic pain and reduces welfare in dogs. Standard treatments may be inadequate or associated with adverse effects, prompting investigation of alternative therapies. Transcutaneous electrical nerve stimulation (TENS) is a non‐pharmacological pain management method, but evidence for its efficacy in canine ...
Anja Pedersen, Johanna Penell, Emil Olsen, Heli Hyytiäinen, Franck Forterre, Anna Bergh   +5 more
wiley   +1 more source

Methodological Quality Evaluation and Comprehensive Analysis of Clinical Practice Guidelines and Expert Consensus for Lumbar Disc Herniation [PDF]

Zhongguo quanke yixue
Background Lumbar disc herniation is one of the most common causes of low back pain, and the number of cases has been increasing year by year in recent years.
QIN Xiaokuan, SUN Kai, FENG Tianxiao, XIAO Xiangyu, WANG Guochen, SU Xiangfei, WEI Xu, ZHU Liguo
doaj   +1 more source

MRI Evaluation of Lumbar Disc Degenerative Disease [PDF]

, 2015
Introduction: Lower back pain secondary to degenerative disc disease is a condition that affects young to middle-aged persons with peak incidence at approximately 40 y.
Mehta, Chetan, Patel, Narrotam, Patel, Rupal, Suthar, Pokhraj   +3 more
core   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Surgical Treatment of Far Lateral Lumbar Disc Herniation: Outcomes of the Safe and Simple Midline Approach [PDF]

, 2022
Mustafa Kaya, Emrah Keskin, Davut Ceylan, Tibet Kaçıra, Özlem Kitiki Kacira   +4 more
openalex   +1 more source

Harnessing Metabolic Priming to Engineer Human Nucleus Pulposus Macromass Overcoming Scalability‐Phenotype Tradeoff

Cell Proliferation, EarlyView.
Human platelet lysate acts as a metabolic primer for hNPCs, enhancing fatty acid oxidation to drive proliferation while preserving phenotype. This enables construction of high‐quality, large‐size macromasses without necrotic defects, demonstrating exceptional efficacy in repairing degenerated discs in situ and providing a novel paradigm for ...
Yingbo Wang, Ou Hu, Jian Wu, Sha Huang, Peng Lin, Pulin Yan, Yangyang Li, Huaijian Jin, Yutong Wu, Jun Zhu, Jungang Pu, Bo Hu, Jian He, Yibo Gan, Peng Liu   +14 more
wiley   +1 more source