Results 21 to 30 of about 139,885 (262)

A Comprehensive Review of Group-III Nitride Light-Emitting Diodes: From Millimeter to Micro-Nanometer Scales

Micromachines
This review describes the development history of group-III nitride light-emitting diodes (LEDs) for over 30 years, which has achieved brilliant achievements and changed people′s lifestyles.
Xinye Fan, Jiawang Shi, Yiren Chen, Guoqing Miao, Hong Jiang, Hang Song   +5 more
doaj   +1 more source

A Design of High-Efficiency: Vertical Accumulation Modulators Based on Silicon Photonics

Nanomaterials, 2023
On-chip optical modulators, which are capable of converting electrical signals into optical signals, constitute the foundational components of photonic devices.
Zhipeng Zhou, Zean Li, Cheng Qiu, Yongyi Chen, Yingshuai Xu, Xunyu Zhang, Yiman Qiao, Yubing Wang, Lei Liang, Yuxin Lei, Yue Song, Peng Jia, Yugang Zeng, Li Qin, Yongqiang Ning, Lijun Wang   +15 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Interferometric Wavefront Sensing System Based on Deep Learning

Applied Sciences, 2020
At present, most wavefront sensing methods analyze the wavefront aberration from light intensity images taken in dark environments. However, in general conditions, these methods are limited due to the interference of various external light sources.
Yuhao Niu, Zhan Gao, Chenjia Gao, Jieming Zhao, Xu Wang   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Phase-pure ferroelectric quantum wells with tunable photoluminescence for multi-state optoelectronic applications

Light: Science & Applications
Quasi-two-dimensional (quasi-2D) metal halide perovskite (MHP) ferroelectrics, characterized by spontaneous polarization and semiconducting properties, hold promise for functional photoferroelectrics in applications such as optical storage and in-memory ...
Rui Sun, Yuping Jia, Bo Lai, Zhiming Shi, Mingrui Liu, Weili Yu, Ke Jiang, Shanli Zhang, Shunpeng Lv, Yang Chen, Xiaojuan Sun, Dabing Li   +11 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Versatile on-chip polarization-sensitive detection system for optical communication and artificial vision

Light: Science & Applications
Polarization is an important attribute of light and can be artificially modulated as a versatile information carrier. Conventional polarization-sensitive photodetection relies on a combination of polarizing optical elements and standard photodetectors ...
Zhilin Liu, Mingxiu Liu, Liujian Qi, Nan Zhang, Bin Wang, Xiaojuan Sun, Rongjun Zhang, Dabing Li, Shaojuan Li   +8 more
doaj   +1 more source

Advancements in Key Parameters of Frequency-Modulated Continuous-Wave Light Detection and Ranging: A Research Review

Applied Sciences
As LiDAR technology progressively advances, the capability of radar in detecting targets has become increasingly vital across diverse domains, including industrial, military, and automotive sectors.
Zibo Wu, Yue Song, Jishun Liu, Yongyi Chen, Hongbo Sha, Mengjie Shi, Hao Zhang, Li Qin, Lei Liang, Peng Jia, Cheng Qiu, Yuxin Lei, Yubing Wang, Yongqiang Ning, Jinlong Zhang, Lijun Wang   +15 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source