Results 31 to 40 of about 229,927 (317)

Time-resolved luminescence spectroscopy of ultrafast emissions in BaGeF6

open access: yes, 2022
Phase-pure crystalline micropowder samples of BaGeF6 were prepared and studied under excitation by tuneable synchrotron radiation and 10 keV electron beam. Time-resolved photoluminescence emission and excitation spectra and a set of single emission decay
Nagirnyi, Vitali   +26 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Interferometric Wavefront Sensing System Based on Deep Learning

open access: yesApplied Sciences, 2020
At present, most wavefront sensing methods analyze the wavefront aberration from light intensity images taken in dark environments. However, in general conditions, these methods are limited due to the interference of various external light sources.
Yuhao Niu   +4 more
doaj   +1 more source

A Design of High-Efficiency: Vertical Accumulation Modulators Based on Silicon Photonics

open access: yesNanomaterials, 2023
On-chip optical modulators, which are capable of converting electrical signals into optical signals, constitute the foundational components of photonic devices.
Zhipeng Zhou   +15 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Phase-pure ferroelectric quantum wells with tunable photoluminescence for multi-state optoelectronic applications

open access: yesLight: Science & Applications
Quasi-two-dimensional (quasi-2D) metal halide perovskite (MHP) ferroelectrics, characterized by spontaneous polarization and semiconducting properties, hold promise for functional photoferroelectrics in applications such as optical storage and in-memory ...
Rui Sun   +11 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Versatile on-chip polarization-sensitive detection system for optical communication and artificial vision

open access: yesLight: Science & Applications
Polarization is an important attribute of light and can be artificially modulated as a versatile information carrier. Conventional polarization-sensitive photodetection relies on a combination of polarizing optical elements and standard photodetectors ...
Zhilin Liu   +8 more
doaj   +1 more source

Advancements in Key Parameters of Frequency-Modulated Continuous-Wave Light Detection and Ranging: A Research Review

open access: yesApplied Sciences
As LiDAR technology progressively advances, the capability of radar in detecting targets has become increasingly vital across diverse domains, including industrial, military, and automotive sectors.
Zibo Wu   +15 more
doaj   +1 more source

In-Service Detection and Quantification of Railway Wheel Flat by the Reflective Optical Position Sensor

open access: yesSensors, 2020
Railway wheel tread flat is one of the main faults of railway wheels, which brings great harm to the safety of vehicle operation. In order to detect wheel flats dynamically and quantitatively when trains are running at high speed, a new wheel flat ...
Run Gao   +3 more
doaj   +1 more source

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