Results 41 to 50 of about 151,628 (269)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Laminating Fabrication of Bifacial Organic-Inorganic Perovskite Solar Cells

International Journal of Photoenergy, 2020
Bifacial solar cells based on organic-inorganic perovskite are fabricated with a laminating process. The structure of the devices is ITO/SnO2/CH3NH3PbI3/NiOx/ITO, in which both electrodes are the transparent ITO layer.
Yujing Yang, Yue Zhu, Xiaoxiao Wang, Qi Song, Chao Ji, Huimin Zhang, Zhiqun He, Chunjun Liang   +7 more
doaj   +1 more source

In-Service Detection and Quantification of Railway Wheel Flat by the Reflective Optical Position Sensor

Sensors, 2020
Railway wheel tread flat is one of the main faults of railway wheels, which brings great harm to the safety of vehicle operation. In order to detect wheel flats dynamically and quantitatively when trains are running at high speed, a new wheel flat ...
Run Gao, Qixin He, Qibo Feng, Jianying Cui   +3 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Low-Dark-Current and Wide-Dynamic-Range InGaAs/InAlAs Avalanche Photodiodes with a Dual-Charge Layer

Photonics
This study explores the impact of a dual-charge layer structure on the performance of InGaAs/InAlAs avalanche photodiodes (APDs) with a separate absorption, charge, multiplication, charge, and transit (SACMCT) structure. The dual-charge layer, consisting
Guohao Yang, Tianhong Liu, Jinping Li, Cunzhu Tong   +3 more
doaj   +1 more source

Simultaneous Measurement of 6DOF Motion Errors of Linear Guides of CNC Machine Tools Using Different Modes

Sensors, 2020
Based on the prior work on the six degrees of freedom (6DOF) motion errors measurement system for linear axes, and for the different types of machine tools and different installation methods, this study used a ray tracing idea to establish the ...
Peizhi Jia, Bin Zhang, Qibo Feng, Fajia Zheng   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Simulation of Modal Control of Metal Mode-Filtered Vertical-Cavity Surface-Emitting Laser

Sensors
In this study, a novel metal-dielectric film mode filter structure that can flexibly regulate the transverse mode inside vertical-cavity surface-emitting lasers (VCSELs) is proposed.
Jingfei Mu, Yinli Zhou, Chao Chen, Xing Zhang, Jianwei Zhang, Tianjiao Liu, Zhuo Zhang, Yuehui Xu, Gaohui Yuan, Jiye Zhang, Yongqiang Ning, Lijun Wang   +11 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

NIR‐I Activated Orthogonal NIR‐IIb/c Emissions in a Lanthanide‐Doped Nanoparticle for Fluorescence Imaging and Information Encryption

Advanced Science
Applying the orthogonal principle for distinguishable second near‐infrared (NIR‐II) emissions has brought new dimensions for ratio fluorescence imaging (RFI) detection and information encryption, deepening the tissue detection depth and improving signal ...
Qiqing Li, Yuanping Huang, Haoyu Zhu, Yaqi Zhu, Yuexi Yi, Xiaodan Li, Haoran Chen, Bin Li, Dabing Li, Yulei Chang   +9 more
doaj   +1 more source