Results 21 to 30 of about 151,628 (269)

Digital Shearing Speckle Pattern Interferometry Based on Rochon Prism and Its Application

Applied Sciences, 2019
This paper presents improved digital shearing speckle pattern interferometry based on Rochon Prism. The advantage of this method is that it avoids the shadow noise caused by transmission light, which improves the shearography accuracy.
Xu Wang, Zhan Gao, Chenjia Gao, Jieming Zhao, Yuhao Niu, Zihui Liu, Yuan Zhang, Yuchen Liu   +7 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Phase-pure ferroelectric quantum wells with tunable photoluminescence for multi-state optoelectronic applications

Light: Science & Applications
Quasi-two-dimensional (quasi-2D) metal halide perovskite (MHP) ferroelectrics, characterized by spontaneous polarization and semiconducting properties, hold promise for functional photoferroelectrics in applications such as optical storage and in-memory ...
Rui Sun, Yuping Jia, Bo Lai, Zhiming Shi, Mingrui Liu, Weili Yu, Ke Jiang, Shanli Zhang, Shunpeng Lv, Yang Chen, Xiaojuan Sun, Dabing Li   +11 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Versatile on-chip polarization-sensitive detection system for optical communication and artificial vision

Light: Science & Applications
Polarization is an important attribute of light and can be artificially modulated as a versatile information carrier. Conventional polarization-sensitive photodetection relies on a combination of polarizing optical elements and standard photodetectors ...
Zhilin Liu, Mingxiu Liu, Liujian Qi, Nan Zhang, Bin Wang, Xiaojuan Sun, Rongjun Zhang, Dabing Li, Shaojuan Li   +8 more
doaj   +1 more source

Nonfullerene Small Molecular Acceptor Acting as a Solid Additive Enables Highly Efficient Pseudo-Bilayer All-Polymer Solar Cells

Energies
In this work, pseudo-bilayer planar heterojunction (PPHJ) all-polymer solar cells (APSCs) were constructed on the basis of the commonly used PY-IT and PM6 as the acceptor and donor, respectively.
Jiayin Liu, Yuheng Ni, Jiaqi Zhang, Yijun Zhao, Wenjing Xu, Xiaoling Ma, Fujun Zhang   +6 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

LUMINESCENCE IN MNEMIOPSIS [PDF]

Journal of General Physiology, 1924
1. In the dark adapted Mnemiopsis, mechanical stimulation causes luminescence along the eight rows of paddle plates. The tactile receptors for this reaction lie only in the paddle plate rows, and are connected only longitudinally along these rows. 2.
openaire   +2 more sources

Advancements in Key Parameters of Frequency-Modulated Continuous-Wave Light Detection and Ranging: A Research Review

Applied Sciences
As LiDAR technology progressively advances, the capability of radar in detecting targets has become increasingly vital across diverse domains, including industrial, military, and automotive sectors.
Zibo Wu, Yue Song, Jishun Liu, Yongyi Chen, Hongbo Sha, Mengjie Shi, Hao Zhang, Li Qin, Lei Liang, Peng Jia, Cheng Qiu, Yuxin Lei, Yubing Wang, Yongqiang Ning, Jinlong Zhang, Lijun Wang   +15 more
doaj   +1 more source