Results 41 to 50 of about 2,211,257 (305)

Hepatoid Adenocarcinoma of the Lung [PDF]

Galicia Clínica, 2018
We present the case of an 80-year-old patient hospitalized for the study of a lower limb bone lesion. The biopsy of this lesion was suggestive of liver cancer metastasis. However, the study of the liver did not present any local lesion. In the event of an hepatoid tumor, a study of the digestive tract was performed, without detection of neoplasia.
Joana Costa, Pedro Ribeiro, Ana Catarina Lucas, Adriano Rodrigues   +3 more
openaire   +3 more sources

EGFR Mutation Status in Uighur Lung Adenocarcinoma Patients

Chinese Journal of Lung Cancer, 2013
Background and objective Epidermal growth factor receptor (EGFR), a transmembrane protein, is a member of the tyrosine kinase family. Gefitinib, an EGFR tyrosine-kinase inhibitors, has shown a high response rate in the treatment of lung cancer in ...
Li SHAN, Yan ZHANG, Feng ZHAO, Limou ZHENG, Guoqing ZHANG   +4 more
doaj   +1 more source

MEK5 promotes lung adenocarcinoma [PDF]

European Respiratory Journal, 2018
MEK5 acts as an oncogenic driver in mice lung cancer and is pivotal for human lung adenocarcinoma http://ow.ly ...
S?nchez Fern?ndez, Adri?n, Ort?z Ru?z, Mar?a Jes?s, Re-Louhau, Mar?a Florencia, Ramos, Isabel, Blanco-M??ez, ?scar, Lude?a de la Cruz, Mar?a Dolores, Abad Hern?ndez, Mar?a Mar, S?nchez Mart?n, Manuel Adolfo, Pandiella Alonso, Atanasio, Espar?s Ogando, Azucena   +9 more
openaire   +4 more sources

Dermatomyositis Anteceding Lung Adenocarcinoma [PDF]

Cureus, 2020
Dermatomyositis is often presented as paraneoplastic syndrome. The diagnosis of dermatomyositis can prompt clinicians to further investigate the underlying cause, in particular malignancy. This case report illustrates the association of lung adenocarcinoma and dermatomyositis with antecedent presentation of cutaneous and musculoskeletal manifestations,
Noor Aliza Md Tarekh, Rozanah Abdul Rahman, Nor Syahida Yusof, Jin Lee Lim   +3 more
openaire   +2 more sources

Progesterone/Org inhibits lung adenocarcinoma cell growth via membrane progesterone receptor alpha

Thoracic Cancer, 2020
Background The aim of this study was to determine whether progesterone could inhibit the growth of lung adenocarcinoma cells via membrane progesterone receptor alpha (mPRα) and elucidate its potential mechanism.
Jian Xiao, Xi Chen, Xiaoxiao Lu, Mingxuan Xie, Bixiu He, Shuya He, Shaojin You, Qiong Chen   +7 more
doaj   +1 more source

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

Nature Genetics, 2020
Brain metastases from lung adenocarcinoma (BM-LUAD) frequently cause patient mortality. To identify genomic alterations that promote brain metastases, we performed whole-exome sequencing of 73 BM-LUAD cases.
D. Shih, D. Shih, Naema Nayyar, Ivanna V. Bihun, Ivanna V. Bihun, I. Dagogo-Jack, C. Gill, C. Gill, Elisa Aquilanti, Elisa Aquilanti, Mia S Bertalan, Alexander Kaplan, M. D’Andrea, U. Chukwueke, F. M. Ippen, C. Alvarez-Breckenridge, Nicholas D. Camarda, Matthew Lastrapes, Devin McCabe, Devin McCabe, Benjamin M Kuter, B. Kaufman, B. Kaufman, M. Strickland, J. Martinez‐Gutierrez, J. Martinez‐Gutierrez, Deepika Nagabhushan, Magali De Sauvage, Michael D. White, Brandyn Castro, Kaitlin Hoang, Andrew Kaneb, Emily Batchelor, S. Paek, S. H. Park, M. Martinez-Lage, A. Berghoff, Parker Merrill, E. Gerstner, T. Batchelor, M. Frosch, Ryan P. Frazier, D. Borger, A. Iafrate, B. Johnson, S. Santagata, S. Santagata, M. Preusser, D. Cahill, S. Carter, P. Brastianos, P. Brastianos   +51 more
semanticscholar   +1 more source

Machine learning of serum metabolic patterns encodes early-stage lung adenocarcinoma

Nature Communications, 2020
Early cancer detection greatly increases the chances for successful treatment, but available diagnostics for some tumours, including lung adenocarcinoma (LA), are limited.
Lin Huang, Lin Wang, Xiaomeng Hu, Sen Chen, Yunwen Tao, Haiyang Su, Jing Yang, W. Xu, V. Vedarethinam, S. Wu, Bin Liu, Xinze Wan, J. Lou, Qian Wang, Kun Qian   +14 more
semanticscholar   +1 more source

Long noncoding RNA expression profiles of lung adenocarcinoma ascertained by microarray analysis. [PDF]

PLoS ONE, 2014
BACKGROUND:Long noncoding RNAs (lncRNAs) have been shown to be involved in the development and progression of lung cancer. However, the roles of lncRNAs in lung cancer are not well understood.
Gang Xu, Jie Chen, Qinshi Pan, Keta Huang, Jingye Pan, Wenhui Zhang, Jian Chen, Fangyou Yu, Tieli Zhou, Yumin Wang   +9 more
doaj   +1 more source

Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics [PDF]

, 2016
Therapeutic manipulation of the gasotransmitter hydrogen sulfide (H(2)S) has recently been proposed as a novel targeted anticancer approach. Here we show that human lung adenocarcinoma tissue expresses high levels of hydrogen sulfide (H(2)S) producing ...
Druzhyna, Nadiya, Hellmich, Mark R., Marcatti, Michela, Nagy, Péter, Szabo, Csaba, Szczesny, Bartosz, Wiktorowicz, John E., Zatarain, John R.   +7 more
core   +1 more source

DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation

Chinese Journal of Lung Cancer, 2021
Background and objective Lung cancer is the leading cause of death worldwide, and lung adenocarcinoma is the main subtype of lung cancer. DEP domain-containing 1 (DEPDC1) has been proved to be closely related to the occurrence and development of most ...
Jian SHEN, Mengmeng XI
doaj   +1 more source