Results 11 to 20 of about 135,036 (309)
Lung deposition of nebulised pentamidine in children. [PDF]
Thorax, 1993 Nebulised pentamidine is effective for preventing Pneumocystis carinii pneumonia in adults with acquired immunodeficiency syndrome. The nebuliser dose required to produce equivalent lung concentrations of pentamidine in children is unknown. This study was performed to measure pulmonary pentamidine deposition in children and to relate this to age ...
Michael O’Doherty +7 more
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Aerosol Deposition in the Lungs of Space Travellers [PDF]
Nature, 1966 THE deposition of aerosols in the lungs of man during breathing constitutes an important mechanism for the entry of toxins or pathogenic organisms to the body. The respiratory tract is protected by an efficient ciliary mechanism for the rapid removal of particles deposited in the upper airways.
D. C. F. Muir
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The Effect of Heterogeneity of Lung Structure on Particle Deposition in the Rat Lung [PDF]
Toxicological Sciences, 2000 Differences in particle deposition patterns between human and rat lungs may be attributed primarily to their differences in breathing patterns and airway morphology. Heterogeneity of lung structure is expected to impact acinar particle deposition in the rat.
W. Hofmann
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FACTORS THAT AFFECT THE LUNG DEPOSITION [PDF]
International Journal of Modern Physics: Conference Series, 2013 The lung is an external organ forming the site of unwanted material or particles. In order to protect it, the airways have to be highly effective filters and if the particle deposit they need to be cleared. Inhaled particles can cause a variety of diseases. There are various factors on which the prediction of depositing particles depends, such as age,
Suresh Kumar Singh +3 more
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Radiolabeling Method for Lyophilizate for Dry Powder Inhalation Formulations
Pharmaceutics, 2022 Human lung deposition data is non-mandatory for drug approval but very useful for the development of orally inhaled drug products. Lung deposition of inhaled drugs can be quantified by radionuclide imaging, for which one of the first considerations is ...
Kahori Miyamoto +2 more
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Numerical Simulation of Particle Motions in Cascade Impactor and Human Respiratory System [PDF]
MATEC Web of Conferences, 2021 Dry powder inhalations (DPIs) have gathered attention as a treatment for respiratory diseases due to the large effective absorption area in a human lung. A cascade impactor is generally used to investigate the inhalation performance of DPIs.
Ohsaki Shuji +4 more
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Pharmaceutics, 2020 Nebulization could be a valuable solution to administer drugs to neonates receiving noninvasive respiratory support. Small and irregular tidal volumes and air leaks at the patient interface, which are specific characteristics of this patient population ...
Francesco Tarantini +4 more
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Pharmaceutics, 2023 Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor nebulizer efficiency and low pulmonary deposition.
Robert M. DiBlasi +6 more
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International Journal of COPD, 2021 Baloira A, Abad A, Fuster A, et al. Int J Chron Obstruct Pulmon Dis. 2021;16:1021–1033. Page 1026, left column, fourth paragraph, the text “Inhaler devices are many times classified as low- (30 L/min or below), medium– (~30–60 L ...
Baloira A +9 more
doaj
Regional Inhaled Deposited Dose of Indoor Combustion-Generated Aerosols in Jordanian Urban Homes
Atmosphere, 2020 Indoor combustion processes associated with cooking, heating, and smoking are a major source of aerosols in Jordanian dwellings. To evaluate human exposure to combustion-generated aerosols in Jordanian indoor environments, regional inhaled deposited dose
Tareq Hussein +2 more
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