Results 21 to 30 of about 140,021 (164)

Powder Particles and Technologies for Medicine Delivery to the Respiratory System: Challenges and Opportunities

open access: yesKONA Powder and Particle Journal, 2017
The paper discusses essential engineering challenges related to the application of powder medicines for pulmonary delivery as inhaled aerosol. Starting from a physically based description of the complexity of aerosol dynamics inside the respiratory ...
Tomasz R. Sosnowski
doaj   +1 more source

FACTORS THAT AFFECT THE LUNG DEPOSITION [PDF]

open access: yesInternational Journal of Modern Physics: Conference Series, 2013
The lung is an external organ forming the site of unwanted material or particles. In order to protect it, the airways have to be highly effective filters and if the particle deposit they need to be cleared. Inhaled particles can cause a variety of diseases. There are various factors on which the prediction of depositing particles depends, such as age,
SHWETA SANKHALA   +3 more
openaire   +1 more source

Heterogeneous deposition of regular and mentholated little cigar smoke in the lungs of Sprague-Dawley rats

open access: yesParticle and Fibre Toxicology, 2023
Background Quantifying the dose and distribution of tobacco smoke in the respiratory system is critical for understanding its toxicity, addiction potential, and health impacts.
Kaisen Lin   +6 more
doaj   +1 more source

Control of Collagen Deposition in Mammalian Lung

open access: yesExperimental Biology and Medicine, 1995
This review considers the mechanisms controlling collagen deposition in mammalian lung in five different states: normal development, fibrosis, erosion, pneumonectomy, and the steady state. Deposition is the net result of positive and negative processes.
R S, Bienkowski, M G, Gotkin
openaire   +2 more sources

In vitro release and in vivo study of quercetin-loaded alginate-kappa carrageenan pulmospheres

open access: yesJournal of Advanced Pharmaceutical Technology & Research
Some antituberculosis drugs were reported to have adverse effects. The study investigates the use of quercetin pulmospheres as an alternative to traditional antituberculosis drugs.
Dewi Melani Hariyadi   +5 more
doaj   +1 more source

Regional Inhaled Deposited Dose of Urban Aerosols in an Eastern Mediterranean City

open access: yesAtmosphere, 2019
We calculated the regional deposited dose of inhaled particulate matter based on number/mass concentrations in Amman, Jordan. The dose rate was the highest during exercising but was generally lower for females compared to males.
Tareq Hussein   +5 more
doaj   +1 more source

Deposition of Large Particles in Human Lung

open access: yesExperimental Lung Research, 1987
Twenty-four nonsmoking males, all without history of pulmonary disease, were randomly divided into four groups of six subjects each. The subjects in each group inhaled monodisperse Teflon particles labelled with 111In (half-life 2.83 days); 8.2, 11.5, 13.7 and 16.4 micron aerodynamic diameter, respectively.
M, Svartengren   +4 more
openaire   +2 more sources

Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned

open access: yesRespiratory Research, 2021
Delivery of medications to preterm neonates receiving non-invasive ventilation (NIV) represents one of the most challenging scenarios for aerosol medicine.
Federico Bianco   +8 more
doaj   +1 more source

Altered deposition of inhaled nanoparticles in subjects with chronic obstructive pulmonary disease

open access: yesBMC Pulmonary Medicine, 2018
Background Respiratory tract deposition of airborne particles is a key link to understand their health impact. Experimental data are limited for vulnerable groups such as individuals with respiratory diseases.
Jonas K F Jakobsson   +6 more
doaj   +1 more source

In Silico Quantification of Intersubject Variability on Aerosol Deposition in the Oral Airway

open access: yesPharmaceutics, 2023
The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition.
Azadeh A. T. Borojeni   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy