Results 21 to 30 of about 135,036 (309)
Pulmonary drug delivery strategies: A concise, systematic review
Lung India, 2012 Because of limitations associated with the conventional treatment of various chronic diseases a growing attention has been given to the development of targeted drug delivery systems. Pulmonary route of drug delivery gaining much importance in the present
J S Patil, S Sarasija
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Biological Obstacles for Identifying In Vitro-In Vivo Correlations of Orally Inhaled Formulations
Pharmaceutics, 2019 Oral inhalation of drugs is the classic therapy of obstructive lung diseases. In contrast to the oral route, the link between in vitro and in vivo findings is less well defined and predictive models and parameters for in vitro-in vivo correlations are ...
Eleonore Fröhlich
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KONA Powder and Particle Journal, 2017 The paper discusses essential engineering challenges related to the application of powder medicines for pulmonary delivery as inhaled aerosol. Starting from a physically based description of the complexity of aerosol dynamics inside the respiratory ...
Tomasz R. Sosnowski
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AtmosphereAirborne particulate matter is a major pollutant globally due to its impact on atmospheric processes and human health. Depending on their aerodynamic size, particles can penetrate the respiratory system, with ultrafine particles (UFPs) reaching the ...
Fabian L. Moreno Camacho +6 more
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Regional Inhaled Deposited Dose of Urban Aerosols in an Eastern Mediterranean City
Atmosphere, 2019 We calculated the regional deposited dose of inhaled particulate matter based on number/mass concentrations in Amman, Jordan. The dose rate was the highest during exercising but was generally lower for females compared to males.
Tareq Hussein +5 more
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Particle and Fibre Toxicology, 2023 Background Quantifying the dose and distribution of tobacco smoke in the respiratory system is critical for understanding its toxicity, addiction potential, and health impacts.
Kaisen Lin +6 more
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Airway Resistance and Deposition of Particles in the Lung
Experimental Lung Research, 1984 The percentage 24-h lung retention of 4-micrometers monodispersed Teflon particles, aerodynamic diameter about 6 micrometers, was studied twice in 8 healthy nonsmokers. The particles were inhaled at 0.5 liter/sec with maximally deep breaths. Bronchoconstriction was induced by inhalation of a methacholine-bromide aerosol for one exposure before and for ...
Per Camner +3 more
openaire +3 more sources
In vitro release and in vivo study of quercetin-loaded alginate-kappa carrageenan pulmospheres
Journal of Advanced Pharmaceutical Technology & ResearchSome antituberculosis drugs were reported to have adverse effects. The study investigates the use of quercetin pulmospheres as an alternative to traditional antituberculosis drugs.
Dewi Melani Hariyadi +5 more
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FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Control of Collagen Deposition in Mammalian Lung
Experimental Biology and Medicine, 1995 This review considers the mechanisms controlling collagen deposition in mammalian lung in five different states: normal development, fibrosis, erosion, pneumonectomy, and the steady state. Deposition is the net result of positive and negative processes.
Robert S. Bienkowski +2 more
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