Results 21 to 30 of about 2,086,066 (301)
The development of the bioartificial lung [PDF]
British Medical Bulletin, 2013 The incidence of chronic lung disease is increasing worldwide due to the spread of risk factors and ageing population. An important advance in treatment would be the development of a bioartificial lung where the blood-gas exchange surface is manufactured from a synthetic or natural scaffold material that is seeded with the appropriate stem or ...
Greg, Lemon +3 more
openaire +2 more sources
Sterilization of lung matrices by supercritical carbon dioxide [PDF]
, 2016 Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L +10 more
core +2 more sources
EMBO Molecular Medicine, 2019 Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth characterized by arrested lung alveolarization, which generates lungs that are incompetent for effective gas exchange.
Jordi Ruiz‐Camp +15 more
doaj +1 more source
Assessment of pulmonary edema: principles and practice [PDF]
, 2018 Pulmonary edema increasingly is recognized as a perioperative complication affecting outcome. Several risk factors have been identified, including those of cardiogenic origin, such as heart failure or excessive fluid administration, and those related to ...
Assaad, Sherif +4 more
core +1 more source
Immunotherapy of lung cancer: An update [PDF]
, 2006 In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced ...
Aman MJ +36 more
core +1 more source
Nature Communications, 2018 Cardiac progenitor cells (CPCs) form cardiomyocytes, pericytes, smooth muscle and endothelial cells during embryonic development. Here, the authors characterize mouse CPCs marked by Nkx2.5 and Isl1 from E7.5 to E9.5 by single cell RNA-seq and ATAC-seq ...
Guangshuai Jia +10 more
doaj +1 more source
Lung Development in the Child [PDF]
American Physical Education Review, 1902 The prominence of affections of the lungs in various diseases, either as complications or primary elements, gives this organ perhaps a higher importance than any other organ in the body. The emphasis given to tuberculosis is not the result of a mere scare, nor is the fear of it to be characterized as a simple "phthisiophobia" without sufficient ...
openaire +2 more sources
Canonical Sonic Hedgehog Signaling in Early Lung Development
Journal of Developmental Biology, 2017 The canonical hedgehog (HH) signaling pathway is of major importance during embryonic development. HH is a key regulatory morphogen of numerous cellular processes, namely, cell growth and survival, differentiation, migration, and tissue polarity. Overall,
Hugo Fernandes-Silva +2 more
doaj +1 more source
Epigenetic silencing of downstream genes mediated by tandem orientation in lung cancer
Scientific Reports, 2017 Epigenetic deregulation is of importance in tumorigenesis. In particular CpG islands (CGI), are frequently hypermethylated. Here, genome-wide DNA-methylation profiles of 480,000 CpGs in lung cancer cells were generated.
Steffen Kiehl +6 more
doaj +1 more source
Animal models, learning lessons to prevent and treat neonatal chronic lung disease
Frontiers in Medicine, 2015 Chronic lung disease (bronchopulmonary dysplasia – BPD) is a consequence of the integrated effects of antenatal exposures, very preterm birth, and postnatal interventions that injure the very immature lung at the saccular stage of lung development ...
Alan H. Jobe
doaj +1 more source