Results 41 to 50 of about 113,160 (301)

Respiratory Fungal Diseases in Adult Patients With Cystic Fibrosis

open access: yesClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2019
Clinical manifestations of respiratory fungal diseases in adult cystic fibrosis (CF) patients are very heterogeneous, ranging from asymptomatic colonization to chronic infections, allergic disorders, or invasive diseases in immunosuppressed CF patients ...
Emanuele Delfino   +4 more
doaj   +1 more source

Two cases of cavitary lung cancer with concomitant chronic infectious disease

open access: yesRespiratory Medicine Case Reports, 2018
The existence of a lung cavity on chest radiographs suggests the presence of lung disease, including benign or malignant disease. Lung cancer, tuberculosis, and fungal infection are all known for developing lung cavity.
Kohei Fujita   +7 more
doaj   +1 more source

Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology : a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologique (Grrr-OH) study [PDF]

open access: yes, 2016
Background: Acute respiratory failure (ARF) is the most frequent complication in patients with hematological malignancies and is associated with high morbidity and mortality.
Azoulay, Elie   +19 more
core   +2 more sources

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

open access: yes, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima   +18 more
core  

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation

open access: yesAngewandte Chemie, EarlyView.
The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner   +4 more
wiley   +2 more sources

Not all Nodules Are Cancer and not all Fungal Infections Are Aspergillus

open access: yesActa Médica Portuguesa, 2022
Pithomyces, a dematiaceous fungus, is a common colonizer of dead leaves and stems of many different plants and is associated with facial eczema in some animals.
Ana Fonseca   +3 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

The burden of serious fungal infections in Sierra Leone: a national estimate

open access: yesTherapeutic Advances in Infectious Disease, 2021
Sierra Leone is a small, resource-limited country that has a low national prevalence of human immunodeficiency virus (HIV) and a very high burden of tuberculosis (TB). Fungal diseases are probably common, but poorly documented.
Sulaiman Lakoh   +6 more
doaj   +1 more source

Multicentric Case Series and Literature Review of Coccidioidal Otomastoiditis

open access: yesEmerging Infectious Diseases, 2023
Coccidioidomycosis involving the ear, mastoid bone, or both is uncommon. We describe 5 new cases from the United States and review 4 cases reported in the literature of otomycosis and mastoiditis caused by Coccidioides.
Ilan S. Schwartz   +7 more
doaj   +1 more source

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