Results 31 to 40 of about 113,160 (301)

Lung inflammation by fungus, Bjerkandera adusta isolated from Asian sand dust (ASD) aerosol and enhancement of ovalbumin-induced lung eosinophilia by ASD and the fungus in mice. [PDF]

, 2014
BackgroundBjerkandera adusta (B. adusta) is one of the most important etiological fungi associated with chronic cough. However, precise details of the inflammatory response to exposure are not well understood yet. B.
Arashidani, Keiichi, He, Miao, Ichinose, Takamichi, Kobayashi, Fumihisa, Liu, Boying, Maki, Teruya, Nishikawa, Masataka, Shibamoto, Takayuki, Sun, Guifan, Takano, Hirohisa, Yoshida, Seiichi, Yoshida, Yasuhiro   +11 more
core   +1 more source

Homobifunctional imidoester-modified zinc nano-spindle attenuated hyphae growth of Aspergillus against hypersensitivity responses

iScience, 2023
Summary: Fungi cause various forms of invasive fungal disease (IFD), and fungal sensitization can contribute to the development of asthma, asthma severity, and other hypersensitivity diseases, such as atopic dermatitis (AD). In this study, we introduce a
Huifang Liu, KeLun Zhang, Yoon Ok Jang, Zhen Qiao, Jie Jin, Thuy Nguyen Thi Dao, Bonhan Koo, Chang Ook Park, Yong Shin   +8 more
doaj   +1 more source

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis. [PDF]

, 2020
There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of ...
Alkhazraji, Sondus, Alqarihi, Abdullah, Gebremariam, Teclegiorgis, Gu, Yiyou, Ibrahim, Ashraf S, Mamouei, Zeinab, Shaw, Karen J, Singh, Shakti, Wiederhold, Nathan P   +8 more
core   +1 more source

Disseminated Scedosporium apiospermum central nervous system infection after lung transplantation: A case report with successful recovery

Medical Mycology Case Reports, 2019
Scedosporium species are fungal opportunistic pathogens frequently seen in chronic lung diseases such as in cystic fibrosis (CF). They can cause a wide spectrum of diseases mainly in immunodeficient patients.
Juuso Paajanen, Maija Halme, Maarit Palomäki, Veli-Jukka Anttila   +3 more
doaj   +1 more source

Allergic bronchopulmonary aspergillosis: diagnostic and treatment challenges [PDF]

, 2016
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder, occurring mostly in asthmatic and cystic fibrosis patients, caused by an abnormal T-helper 2 lymphocyte response of the host to Aspergillus fumigatus antigens.
CINICOLA, BIANCA LAURA, DUSE, MARZIA, Laitano, Rossella, LEONARDI, LUCIA   +3 more
core   +1 more source

Reciprocal Inhibition of Adiponectin and Innate Lung Immune Responses to Chitin and Aspergillus fumigatus [PDF]

, 2019
Chitin is a structural biopolymer found in numerous organisms, including pathogenic fungi, and recognized as an immune-stimulating pathogen associated molecular pattern by pattern recognition molecules of the host immune system.
Amarsaikhan, Nansalmaa, Gravely, Haley, Sands, Ethan M., Stolz, Dylan J., Templeton, Steven P., Tsoggerel, Angar, Wilcox, Amber   +6 more
core   +4 more sources

Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. [PDF]

, 2014
UnlabelledCryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system.
Bautos, Jennifer M, Gelli, Angie, Jamklang, Mantana, Na Pombejra, Sarisa, Tham, Rick, Thompson, George R, Uhrig, John P, Vu, Kiem   +7 more
core   +2 more sources

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

A survey of fungal microbiota in airways of healthy volunteer subjects from Puglia (Apulia), Italy

BMC Infectious Diseases, 2019
Background The human respiratory tract represents the major portal of entry for numerous microorganisms, primarily those occurring as airborne particles such as viral and bacterial entities, or fungal spores.
Giovanna Elisiana Carpagnano, Antonia Susca, Giulia Scioscia, Donato Lacedonia, Grazia Cotugno, Piera Soccio, Sonia Santamaria, Onofrio Resta, Giuseppe Logrieco, Maria Pia Foschino Barbaro   +9 more
doaj   +1 more source

Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy [PDF]

, 2016
A case of pleuropneumonia is reported in an adult male bottlenose dolphin (Tursiops truncatus) found stranded in 2014 along the Central Adriatic coast of Italy.
Camm\ue0, Cesare, Curini, Valentina, Di Francesco, Cristina Esmeralda, Di Francesco, Gabriella, Di Guardo, Giovanni, Di Provvido, Andrea, Ferri, Nicola, Mazzariol, Sandro, Proietto, Umberto   +8 more
core   +1 more source