Results 61 to 70 of about 11,428,692 (412)

Novel folliculin gene mutations in Polish patients with Birt–Hogg–Dubé syndrome

open access: yesOrphanet Journal of Rare Diseases, 2021
Background Birt–Hogg–Dubé syndrome (BHDS) is a rare, autosomal dominant, inherited disease caused by mutations in the folliculin gene (FLCN). The disease is characterised by skin lesions (fibrofolliculomas, trichodiscomas, acrochordons), pulmonary cysts ...
Elżbieta Radzikowska   +3 more
doaj   +1 more source

Large Pericardial Effusion—Diagnostic and Therapeutic Options, with a Special Attention to the Role of Prolonged Pericardial Fluid Drainage

open access: yesDiagnostics, 2022
Background: Large pericardial effusion (LPE) is associated with high mortality. In patients with cardiac tamponade or with suspected bacterial etiology of pericardial effusion, urgent pericardial decompression is necessary.
Małgorzata Dybowska   +7 more
doaj   +1 more source

Elastocapillary network model of inhalation [PDF]

open access: yesPhysical Review Research, 2, 043382 (2020), 2020
The seemingly simple process of inhalation relies on a complex interplay between muscular contraction in the thorax, elasto-capillary interactions in individual lung branches, propagation of air between different connected branches, and overall air flow into the lungs.
arxiv   +1 more source

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]

open access: yes, 2014
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu   +4 more
core   +2 more sources

Developing inhaled protein therapeutics for lung diseases

open access: yesMolecular Biomedicine, 2020
Biologic therapeutics such as protein/polypeptide drugs are conventionally administered systemically via intravenous injection for the treatment of diseases including lung diseases, although this approach leads to low target site accumulation and the ...
A. Matthews, P. L. Ee, R. Ge
semanticscholar   +1 more source

Interstitial lung disease [PDF]

open access: yesEuropean Respiratory Review, 2013
This article reviews the most important articles published in interstitial lung disease, as reviewed during the Clinical Year in Review session at the 2012 annual European Respiratory Society Congress in Vienna, Austria.Since the recent international guidelines for the management of idiopathic pulmonary fibrosis (IPF), important new evidence is ...
openaire   +4 more sources

A multicentre retrospective observational study on Polish experience of pirfenidone therapy in patients with idiopathic pulmonary fibrosis: the PolExPIR study

open access: yesBMC Pulmonary Medicine, 2020
Background Pirfenidone is an antifibrotic agent approved for the treatment of idiopathic pulmonary fibrosis (IPF). The drug is available for Polish patients with IPF since 2017. The PolExPIR study aimed to describe the real-world data (RWD) on the Polish
Sebastian Majewski   +25 more
doaj   +1 more source

MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro [PDF]

open access: yes, 2012
Possession of a properly functioning innate immune system in the lung is vital to prevent infections due to the ongoing exposure of the lung to pathogens.
Amit Gaggar   +6 more
core   +3 more sources

Tobacco Smoke Induces and Alters Immune Responses in the Lung Triggering Inflammation, Allergy, Asthma and Other Lung Diseases: A Mechanistic Review

open access: yesInternational Journal of Environmental Research and Public Health, 2018
Many studies have been undertaken to reveal how tobacco smoke skews immune responses contributing to the development of chronic obstructive pulmonary disease (COPD) and other lung diseases. Recently, environmental tobacco smoke (ETS) has been linked with
Agnieszka Strzelak   +3 more
semanticscholar   +1 more source

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