Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Automated Segmentation of Pulmonary Lobes using Coordination-Guided Deep Neural Networks
The identification of pulmonary lobes is of great importance in disease diagnosis and treatment. A few lung diseases have regional disorders at lobar level. Thus, an accurate segmentation of pulmonary lobes is necessary.
Chen, Junxuan +6 more
core +1 more source
Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Adamson IY +66 more
core +1 more source
Correction to: Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis
After publication of our article [1] the authors have notified us that one of the names has been incorrectly tagged.
David Bennett +14 more
doaj +1 more source
COVID-19, A New Possible Mimicker of Interstitial Lung Disease Related to Primary Sjögren’s Syndrome
Introduction. Acute exacerbation of interstitial lung disease (ILD) and COVID-19 pneumonia show many similarities, but also COVID-19 sequelae, mainly when fibrotic features are present, can be difficult to distinguish from chronic ILD observed in ...
Alessia Laneri +7 more
doaj +1 more source
Self-proning in COVID-19 patients on low-flow oxygen therapy: a cluster randomised controlled trial
Rationale and objectives Prone positioning as a complement to oxygen therapy to treat hypoxaemia in coronavirus disease 2019 (COVID-19) pneumonia in spontaneously breathing patients has been widely adopted, despite a lack of evidence for its benefit.
Aileen Kharat +10 more
doaj +1 more source
Fused Weighted Federated Deep Extreme Machine Learning Based on Intelligent Lung Cancer Disease Prediction Model for Healthcare 5.0 [PDF]
Sagheer Abbas +7 more
openalex +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Airway involvement in interstitial lung disease [PDF]
PURPOSE OF REVIEW: After briefly discussing several ways to approach airway involvement in interstitial lung diseases - by diagnostic methodologies used to assess it, considering different topographical involvement, related to its presence in the diffuse
Robalo-Cordeiro, C
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source

