Results 31 to 40 of about 1,833,864 (358)

The value of high-resolution computed tomography (HRCT) to determine exercise ventilatory inefficiency and dynamic hyperinflation in adult patients with cystic fibrosis

Respiratory Research, 2019
Introduction In Cystic Fibrosis (CF), exercise ventilatory inefficiency and dynamic hyperinflation (DH) cause exercise limitation and induce poor exercise tolerance.
Ernesto Crisafulli, Elisabetta Teopompi, Silvia Luceri, Francesco Longo, Panagiota Tzani, Paolo Pagano, Antonella Ielpo, Chiara Longo, Marcello Di Paolo, Nicola Sverzellati, Paolo Palange, Alfredo Chetta, Giovanna Pisi   +12 more
doaj   +1 more source

Cardiac mechanics and reverse remodelling under mechanical support from left ventricular assist devices

Frontiers in Cardiovascular Medicine, 2023
In recent years, development of mechanical circulatory support devices has proved to be a new treatment modality, in addition to standard pharmacological therapy, for patients with heart failure or acutely depressed cardiac function.
Blanca Pamias-Lopez, Michael E. Ibrahim, Fotios G. Pitoulis, Fotios G. Pitoulis   +3 more
doaj   +1 more source

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]

, 2013
Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan, Borchers, Christoph H., Brodsky, Kelley, Eckle, Tobias, Eltzschig, Holger K., Han, Jun, Kominsky, Douglas J., Mariani, Thomas J., Mittelbronn, Michel Guy André, Packard, Thomas   +9 more
core   +3 more sources

Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices

Scientific Reports, 2018
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures.
Rasheda A. Chowdhury, Konstantinos N. Tzortzis, Emmanuel Dupont, Shaun Selvadurai, Filippo Perbellini, Chris D. Cantwell, Fu Siong Ng, Andre R. Simon, Cesare M. Terracciano, Nicholas S. Peters   +9 more
doaj   +1 more source

Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage

Respirology Case Reports, 2020
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was ...
Ernesto Crisafulli, Barbara Burgazzi, Maria Majori, Walter Serra, Alfredo Chetta   +4 more
doaj   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

Frontiers in Physiology, 2018
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains.
Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik   +9 more
doaj   +1 more source

Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

Respiratory Research, 2023
Introduction The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of life are major issues in the ...
Jules Milesi, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon, Benjamin Coiffard   +7 more
doaj   +1 more source

Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]

, 2010
Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H., Denai, M., Mahfouf, M., Mills, G.H., Mohamad-Samuri, S., Panoutsos, G.   +5 more
core   +2 more sources

Regulation of Immunoproteasome Function in the Lung [PDF]

Scientific Reports, 2015
AbstractImpaired immune function contributes to the development of chronic obstructive pulmonary disease (COPD). Disease progression is further exacerbated by pathogen infections due to impaired immune responses. Elimination of infected cells is achieved by cytotoxic CD8+  T cells that are activated by MHC I-mediated presentation of pathogen-derived ...
Keller, I.E., Vosyka, O., Takenaka, S., Kloss, A., Dahlmann, B., Willems, L.I., Verdoes, M., Overkleeft, H.S., Marcos, E., Adnot, S., Hauck, S.M., Ruppert, C., Guenther, A., Herold, S., Ohno, S., Adler, H., Eickelberg, O., Meiners, S.   +17 more
openaire   +8 more sources

SARS-CoV-2 Neutralizing Antibodies: A Network Meta-Analysis across Vaccines

Vaccines, 2021
Background: There are no studies providing head-to-head comparison across SARS-CoV-2 vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing neutralizing antibodies against SARS-CoV-2.
Paola Rogliani, Alfredo Chetta, Mario Cazzola, Luigino Calzetta   +3 more
doaj   +1 more source