Results 31 to 40 of about 14,390,763 (310)

Cardiac mechanics and reverse remodelling under mechanical support from left ventricular assist devices

Frontiers in Cardiovascular Medicine, 2023
In recent years, development of mechanical circulatory support devices has proved to be a new treatment modality, in addition to standard pharmacological therapy, for patients with heart failure or acutely depressed cardiac function.
Blanca Pamias-Lopez, Michael E. Ibrahim, Fotios G. Pitoulis, Fotios G. Pitoulis   +3 more
doaj   +1 more source

Lung function trajectories in health and disease.

The Lancet Respiratory Medicine, 2019
The normal lung function trajectory from birth to death has three phases: a growth phase (from birth to early adulthood), a plateau phase (that lasts for a few years), and a decline phase resulting from physiological lung ageing.
A. Agustí, R. Faner
semanticscholar   +1 more source

Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices

Scientific Reports, 2018
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures.
Rasheda A. Chowdhury, Konstantinos N. Tzortzis, Emmanuel Dupont, Shaun Selvadurai, Filippo Perbellini, Chris D. Cantwell, Fu Siong Ng, Andre R. Simon, Cesare M. Terracciano, Nicholas S. Peters   +9 more
doaj   +1 more source

Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage

Respirology Case Reports, 2020
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was ...
Ernesto Crisafulli, Barbara Burgazzi, Maria Majori, Walter Serra, Alfredo Chetta   +4 more
doaj   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

Frontiers in Physiology, 2018
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains.
Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik   +9 more
doaj   +1 more source

Rate of normal lung function decline in ageing adults: a systematic review of prospective cohort studies

BMJ Open, 2019
Objective To conduct a systematic review investigating the normal age-related changes in lung function in adults without known lung disease. Design Systematic review.
E. T. Thomas, Michelle Guppy, S. Straus, K. Bell, P. Glasziou   +4 more
semanticscholar   +1 more source

Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

Respiratory Research, 2023
Introduction The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of life are major issues in the ...
Jules Milesi, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon, Benjamin Coiffard   +7 more
doaj   +1 more source

Lung Development Genes and Adult Lung Function

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Poor lung health in adult life may occur partly through suboptimal growth and development, as suggested by epidemiological evidence pointing to early life risk factors.Objectives: To systematically investigate the effects of lung development genes on adult lung function.Methods: Using UK Biobank data, we tested the association of 391 genes ...
Laura Portas, Miguel Pereira, Seif O. Shaheen, Annah B. Wyss, Stephanie J. London, Peter G. J. Burney, Matthew Hind, Charlotte H. Dean, Cosetta Minelli   +8 more
openaire   +4 more sources

Lung-function trajectories: relevance and implementation in clinical practice.

The Lancet
Lung development starts in utero and continues during childhood through to adolescence, reaching its peak in early adulthood. This growth is followed by gradual decline due to physiological lung ageing. Lung-function development can be altered by several
E. Mélen, R. Faner, James P Allinson, Dinh Bui, Andrew Bush, Adnan Custovic, Judith Garcia-Aymerich, Stefano Guerra, R. Breyer-Kohansal, Jenny Hallberg, L. Lahousse, Fernando D Martinez, S. Merid, Pippa Powell, H. Pinnock, S. Stanojevic, L. Vanfleteren, Gang Wang, S. Dharmage, J. Wedzicha, Àlvar Agustí, A. Abellan, Ian M Adcock, S. Afzal, P. Alter, H. Backman, X. Bertels, Chloe I. Bloom, Klaus Bønnelykke, M. Breyer, S. Casas, Fan Chung, Y. Çolak, B. G. Cosío, L. Duijts, Leonardo Fabbri, S. Fontanella, Elaine Fuertes, Juan R. González, R. Granell, S. Hartl, N. Hernandez-Pacheco, John W. Holloway, Deborah Jarvis, H. Koefoed, T. Kole, Ashish Kumar, A. Langhammer, A. Lindberg, Maria Llopis, A. M. D. Zee, H. Meteran, C. Minelli, B. Nwaru, N. Olvera, G. Peralta, A. Ritchie, E. Rönmark, J. Chapman, Julia Boix, Tamara Schikowski, V. Schlünssen, Seif O Shaheen, T. Sigsgaard, M. Standl, M. Talaei, Anhar Ullah, A. Ullman, C. Valencia-Hernandez, M. Berge, Yoni van Dijk, Jørgen Vestbo, Susanne Vijverberg, S. A. Vikjord, Claus Volgelmeier, Judith M. Vonk, N. Kermani   +76 more
semanticscholar   +1 more source

Childhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life.

The Lancet Respiratory Medicine, 2018
BACKGROUND Lifetime lung function is related to quality of life and longevity. Over the lifespan, individuals follow different lung function trajectories.
D. Bui, C. Lodge, J. Burgess, A. Lowe, J. Perret, M. Bui, G. Bowatte, L. Gurrin, D. Johns, Bruce R Thompson, G. Hamilton, P. Frith, A. James, P. Thomas, D. Jarvis, C. Svanes, M. Russell, S. Morrison, I. Feather, K. Allen, R. Wood-Baker, J. Hopper, G. Giles, M. Abramson, E. Walters, M. Matheson, S. Dharmage   +26 more
semanticscholar   +1 more source