Results 51 to 60 of about 164,398 (291)

Cardiac Imaging in Patients After Fontan Palliation: Which Test and When?

Frontiers in Pediatrics, 2022
The Fontan operation represents the final stage of a series of palliative surgical procedures for children born with complex congenital heart disease, where a “usual” biventricular physiology cannot be restored.
Paolo Ciliberti, Paolo Ciancarella, Pasqualina Bruno, Davide Curione, Veronica Bordonaro, Veronica Lisignoli, Mario Panebianco, Marcello Chinali, Aurelio Secinaro, Lorenzo Galletti, Paolo Guccione   +10 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Medium term results following heart transplantation for end stage heart failure: A single center experience of 257 patients

Indian Heart Journal, 2020
Objective: End stage heart failure is a lethal disease with a dismal 5 year survival. Heart transplantation has proven to be a highly effective modality of treatment in appropriately selected group of such patients.
K.R. Balakrishnan, K.G. Sureshrao, R. Ravikumar, T. Muralikrishna, K. Ganapathy Subramaniam, R. Mohan, A. Ajay, K. Ramasubramanian, D. Jagdish, R. Veena   +9 more
doaj  

Coronavirus disease 2019 outcomes in heart transplant recipients: a single-center case series

Journal of Medical Case Reports, 2021
Background With the rapidly expanding pandemic of severe acute respiratory syndrome coronavirus-2, a chronic immunosuppressed state in solid organ transplant recipients is a concern. We reported coronavirus disease 2019 in heart transplant recipients and
Farah Naghashzadeh, Shadi Shafaghi, Babak Sharif-Kashani, Payam Tabarsi, Leila Saliminejad, Sima Noorali   +5 more
doaj   +1 more source

Post-Lung Transplantation Outcomes and Ex Vivo Histopathological Findings in Severe Post-Covid-19 Pulmonary Disease-A Single-Center Experience [PDF]

, 2022
BACKGROUND: A significant proportion of patients with severe and persistent coronavirus disease 2019 (COVID-19) require continuous ventilatory support and occasional extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS)
Hasbun, Rodrigo, Javaid, Hana, Jyothula, Soma, Nigo, Masayuki, Ostrosky-Zeichner, Luis, Patel, Manish, Trujillo, Daniel Ocazionez, Zhao, Bihong   +7 more
core   +2 more sources

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

KRT8 Serves as a Novel Biomarker for LUAD and Promotes Metastasis and EMT via NF-κB Signaling

Frontiers in Oncology, 2022
Keratin 8 (KRT8) is the major component of the intermediate filament cytoskeleton and aberrant expression in multiple tumors. However, the role of KRT8 in lung adenocarcinoma (LUAD) remains unclear.
Hao Chen, Xiaobin Chen, Bo Pan, Chutian Zheng, Liangjie Hong, Weili Han   +5 more
doaj   +1 more source

Effect of volume reduction on lung transplant timing and selection for chronic obstructive pulmonary disease [PDF]

, 1998
Background: End-stage chronic obstructive pulmonary disease has traditionally been treated with lung transplantation. For 2 years, our lung transplantation program has placed patients with appropriate criteria for lung transplantation and volume ...
Bavaria, Joseph E., Kaiser, Larry R., Kotloff, Robert M., Palevsky, Harold I., Pochettino, Alberto, Roberts, J., Rosengard, Bruce R., Wahl, Peter M.   +7 more
core   +1 more source

Lung transplantation for emphysema [PDF]

Annals of Translational Medicine, 2020
Lung transplantation (LT) is proved to be effective in patients with end-stage lung disease who are failing optimal therapy. Chronic obstructive pulmonary disease (emphysema) is the most common indication for adult lung transplantation. As most patients with emphysema (EMP) can survive long term, it could be difficult to decide which patient should be ...
openaire   +4 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source