Results 61 to 70 of about 447,886 (300)

Serial fetal lung volume measurement using three‐dimensional ultrasound [PDF]

Ultrasound in Obstetrics & Gynecology, 2000
AbstractObjectiveTo establish reference intervals for fetal lung growth.DesignLongitudinal observational study.SubjectsFifty‐eight women with initially uncomplicated singleton pregnancies were recruited from the antenatal population of a teaching hospital.
Bahmaie, A., Hughes, S. W., Clark, T., Milner, A., Saunders, J., Tilling, K., Maxwell, D. J.   +6 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Distribution of transpulmonary pressure during one-lung ventilation in pigs at different body positions

Frontiers in Physiology, 2023
Background. Global and regional transpulmonary pressure (PL) during one-lung ventilation (OLV) is poorly characterized. We hypothesized that global and regional PL and driving PL (ΔPL) increase during protective low tidal volume OLV compared to two-lung ...
Jakob Wittenstein, Martin Scharffenberg, Xiuli Yang, Xiuli Yang, Thomas Bluth, Thomas Kiss, Thomas Kiss, Marcus J. Schultz, Patricia R. M. Rocco, Paolo Pelosi, Paolo Pelosi, Marcelo Gama de Abreu, Marcelo Gama de Abreu, Marcelo Gama de Abreu, Robert Huhle   +14 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correlation Analysis of the Lung Volume Reduction and the Lung Function Loss 
after the Thoracoscopic Lobectomy

Chinese Journal of Lung Cancer, 2022
Background and objective To investigate the correlation between the reduction of lung volume and the degree of lung function damage after lobectomy. Methods A total of 131 patients (72 males and 59 females) who underwent thoracoscopic lobectomy in the ...
Zhenzhou ZHAI, Jun ZHAO, Chang LI, Cheng DING, Chun XU   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Flow-Volume Parameters in COPD Related to Extended Measurements of Lung Volume, Diffusion, and Resistance

Pulmonary Medicine, 2013
Classification of COPD into different GOLD stages is based on forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) but has shown to be of limited value.
Linnea Jarenbäck, Jaro Ankerst, Leif Bjermer, Ellen Tufvesson   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Determination of reliable lung function parameters in intubated mice

Respiratory Research, 2019
Background Animal models and, in particular, mice models, are important tools to investigate the pathogenesis of respiratory diseases and to test potential new therapeutic drugs. Lung function measurement is a key step in such investigation.
Eline Bonnardel, Renaud Prevel, Marilyne Campagnac, Marielle Dubreuil, Roger Marthan, Patrick Berger, Isabelle Dupin   +6 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source