Results 41 to 50 of about 345,374 (311)

Lupus anticoagulant is frequent in patients with Covid‐19: Response to Reply

open access: yesJournal of Thrombosis and Haemostasis, 2020
We have recently published in the Journal of Thrombosis and Haemostasis the presence of lupus anticoagulant (LAC) at high frequency in Covid‐19 patients (1). Different authors had confirmed these results (2).
I. Harzallah, A. Debliquis, B. Drénou
semanticscholar   +1 more source

Influence of anticardiolipin and anti-β2 glycoprotein I antibody cutoff values on antiphospholipid syndrome classification [PDF]

open access: yes, 2019
Background: Anticardiolipin (aCL) and anti-beta 2 glycoprotein I (a beta 2GPI) immunoglobulin (Ig) G/IgM antibodies are 2 of the 3 laboratory criteria for classification of antiphospholipid syndrome (APS).
de Laat, Bas   +4 more
core   +3 more sources

The Lupus Anticoagulant

open access: yesExperimental Biology and Medicine, 1984
Lupus-like anticoagulant (LLAC) is the term used to identify an acquired inhibitor (1) of blood coagulation, first described by Conley and Hartmann in patients with systemic lupus erythematosus (SLE) (2). A circulating “lupus-like” anticoagulant has been detected in 5-10% of all SLE patients.
N, Perico, F, Pusineri, G, Remuzzi
openaire   +2 more sources

High prevalence of antinuclear antibodies and lupus anticoagulant in patients hospitalized for SARS-CoV2 pneumonia

open access: yesClinical Rheumatology, 2020
About 15–20% of patients with severe acute respiratory syndrome–coronavirus 2 (SARS-CoV2) disease experience pneumonia of variable extent and course [1]. A proportion of them have cardiovascular involvement, including myocarditis, ischemia and shock, and
C. Gazzaruso   +6 more
semanticscholar   +1 more source

Detection and quantification of lupus anticoagulants in plasma from heparin treated patients, using addition of polybrene

open access: yesThrombosis Journal, 2006
Background Lupus anticoagulants prolong clotting times in phospholipid-dependent coagulation tests. Lupus Ratio assays are integrated tests for lupus anticoagulants that may be based on APTT, RVVT or dPT clotting times. If a patient is being treated with
Wisløff Finn   +3 more
doaj   +1 more source

Loss of antiphospholipid antibody positivity post-thrombosis in SLE

open access: yesLupus Science and Medicine, 2020
Background/Purpose Loss of positivity of antiphospholipid antibodies has been observed in clinical practice post-thrombosis in patients with SLE with secondary antiphospholipid syndrome (APS). Our study defined the frequency of this loss and the duration
Muznay Khawaja
doaj   +1 more source

Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss [PDF]

open access: yes, 2012
Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy.
Brachvogel, Bent   +11 more
core   +1 more source

Direct oral anticoagulant adsorption: Impact on lupus anticoagulant testing—Review of the literature and evaluation on spiked and patient samples

open access: yesJournal of Thrombosis and Haemostasis, 2020
Direct oral anticoagulants (DOACs) interfere with lupus anticoagulant (LAC) testing. DOAC‐Stop (D‐S) represents a preanalytical strategy to cope with this issue.
Pieter M M De Kesel, K. Devreese
semanticscholar   +1 more source

Cognitive dysfunction improves in systemic lupus erythematosus: Results of a 10 years prospective study [PDF]

open access: yes, 2018
Objective Cognitive impairment (CI) has been described in 3–80% of Systemic lupus erythematosus (SLE) patients but only short-term studies evaluated its over-time changes, suggesting that CI is usually a stable finding. We aimed at evaluating the changes
Alessandri, Cristiano   +9 more
core   +2 more sources

Lupus anticoagulant and mortality in patients hospitalized for COVID-19

open access: yesJournal of Thrombosis and Thrombolysis, 2020
Coronavirus disease 2019 (COVID-19) is characterized by a procoagulant state that can lead to fatal thromboembolic events. Several studies have documented a high prevalence of lupus anticoagulant that may at least partially explain the procoagulant ...
C. Gazzaruso   +10 more
semanticscholar   +1 more source

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