Results 81 to 90 of about 2,937 (121)

Lupus anticoagulant: case-based external quality assessment

open access: green, 2009
A.M.H.P. van den Besselaar   +3 more
openalex   +2 more sources

LUPUS ANTICOAGULANT IN PREGNANCY

The Lancet, 1984
summaryIn a group of 10 women with circulating lupus anticoagulant 25 intrauterine deaths were previously documented in the nine multigravidae. The presence of lupus anticoagulant activity was confirmed by showing prolongation of the activated partial thromboplastin time and kaolin clotting time with failure of correction of the prolongation on ...
Prentice, RL   +5 more
openaire   +6 more sources

The lupus anticoagulant

Arthritis & Rheumatism, 1976
AbstractThe clinical and laboratory experience with the lupus anticoagulant was reviewed in 37 patients. The anticoagulant is thought to act by blocking the activation of prothrombin by the prothrombin activator complex of factors Xa, V, and phospholipid.
Michael Boxer   +2 more
openaire   +3 more sources

Lupus anticoagulant

Blood Reviews, 1991
Acquired antibodies to phospholipids form a heterogeneous group, which may be detected in vitro by the inhibition of phospholipid dependent tests of coagulation (lupus anticoagulant) and also by immunological assays, such that a combined approach is required for their reliable detection.
M D, Creagh, M, Greaves
openaire   +2 more sources

The challenges of lupus anticoagulants

Expert Review of Hematology, 2016
The term "lupus anticoagulant" (LA) refers to a heterogeneous group of immunoglobulins behaving as acquired in vitro inhibitors of coagulation. These antibodies, namely anti-β2GPI and anti-prothrombin antibodies, induce the in vitro elongation of clotting time interfering with phospholipid-dependent coagulation cofactors. Positive LA is associated with
C.B. Chighizola   +5 more
openaire   +2 more sources

Lupus Anticoagulant and Stroke

Archives of Neurology, 1987
To the Editor. —Tabachnik-Schor and Lipton's 1 recent report of a case of nonvasculitic cerebral infarction associated with a lupuslike anticoagulant (LA) suggests that their case is the first without "other causes of vasculopathy." Several features of their patient's case do not appear to support their conclusion. Their patient's skin biopsy specimen
Steven R. Levine, K.M.A. Welch
openaire   +3 more sources

Lupus anticoagulant in myelofibrosis

The American Journal of the Medical Sciences, 1976
A patient with myelofibrosis who also demonstrates a lupus anticoagulant is reported. The presence of a circulating anticoagulant adds to the list of potential hemorrhagic diatheses in myelofibrosis and also demonstrates myelofibrosis to involve a system that may be separate from the myeloid elements of the bone marrow.
Bernard Bernhardt, Marie Valletta
openaire   +3 more sources

Lupus anticoagulant and pregnancy

American Journal of Obstetrics and Gynecology, 1985
A subset of women with a high rate of fetal wastage is identifiable among those with serologic but not necessarily clinical evidence of connective tissue disease. The presence of lupus anticoagulant in the plasma of a pregnant woman serves as a marker for a high rate of fetal wastage and risk of thrombosis. Lupus anticoagulant is best identified by the
Graham C. Liggins, Wilhelm F. Lubbe
openaire   +3 more sources

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