Results 31 to 40 of about 19,610 (201)
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]
, 2009 PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra +4 more
core +2 more sources
Nigerian Journal of Medicine, 2019 Background:- Inhibitors to infused factor VIII are the most significant complication of hemophilia treatment. These inhibitors are usually IgG antibodies, that react with FVIII in a time and temperature dependent manner.
Mirza Asif Baig +4 more
doaj +1 more source
Hemostatic disturbances in acute ischemic stroke [PDF]
, 2012 Background: Stroke is the 2nd most common cause of death after ischemic heart disease. About 85% of all strokes are caused by a thrombus or an embolus in the cerebral circulation.
Rooth, Elisabeth
core +1 more source
Pitfalls in hemostasis exploration, a case report of a girl with Henoch-Schönlein type vasculitis
Romanian Journal of Laboratory Medicine, 2017 The adequate performance and correct interpretation of assays for coagulation factor inhibitors play a critical role for the hemostasis laboratory. Both, false positive and false negative inhibitor assays may be reported, leading to erroneous patient’s ...
Arghirescu Smaranda +6 more
doaj +1 more source
An investigation to find the correlation between lupus anticoagulant and coagulation abnormalities in COVID-19 patients; a narrative review [PDF]
Journal of NephropathologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19) which is associated with nonspecific respiratory syndromes, varying from mild symptoms of upper airway to required mechanical ventilation ...
Amir Aria +3 more
doaj +1 more source
Key inflammatory pathway activations in the MCI stage of Alzheimer's disease [PDF]
, 2019 OBJECTIVE: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease (AD).
Bekris, Lynn M. +7 more
core +2 more sources
Frontiers in Immunology, 2018 The Kallikrein–Kinin System (KKS), comprised of kallikreins (klks), bradykinins (BKs) angiotensin-converting enzyme (ACE), and many other molecules, regulates a number of physiological processes, including inflammation, coagulation, angiogenesis, and ...
Alecia Seliga +8 more
doaj +1 more source
Prediction of recurrent venous thromboembolism by clot lysis time: a prospective cohort study. [PDF]
PLoS ONE, 2012 Venous thromboembolism (VTE) is a chronic disease, which tends to recur. Whether an abnormal fibrinolytic system is associated with an increased risk of VTE is unclear.
Ludwig Traby +4 more
doaj +1 more source
Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis
Advanced Science, EarlyView.Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu +13 more
wiley +1 more source