Results 81 to 90 of about 19,420 (199)

Urinary eicosanoid metabolites in HIV-infected women with central obesity switching to raltegravir: an analysis from the women, integrase, and fat accumulation trial. [PDF]

, 2014
Chronic inflammation is a hallmark of HIV infection. Eicosanoids reflect inflammation, oxidant stress, and vascular health and vary by sex and metabolic parameters. Raltegravir (RAL) is an HIV-1 integrase inhibitor that may have limited metabolic effects.
Boger, M Sean, Currier, Judith S, Hulgan, Todd, Lake, Jordan E, Liao, Diana H, Mangili, Alexandra, McComsey, Grace A, McCreath, Heather, Milne, Ginger L, Sanchez, Stephanie C, Walmsley, Sharon L, Wanke, Christine A   +11 more
core   +3 more sources

Haemostatic Parameters in Patients with Behçet’s Disease

Sultan Qaboos University Medical Journal, 2014
Objectives: This study aimed to evaluate the cause of thrombosis in Behçet’s disease (BD) patients, since abnormalities in coagulation and fibrinolytic parameters have shown contradictory results.
Juma K. Alkaabi, David Gravell, Hamood Al-Haddabi, Anil Pathare   +3 more
doaj   +2 more sources

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial. [PDF]

, 2016
BACKGROUND: Rivaroxaban is established for the treatment and secondary prevention of venous thromboembolism, but whether it is useful in patients with antiphospholipid syndrome is uncertain. METHODS: This randomised, controlled, open-label, phase 2/3,
Arachchillage, DR, Bertolaccini, ML, Clawson, S, Cohen, H, Doré, CJ, Efthymiou, M, Hunt, BJ, Isenberg, DA, Khamashta, M, Machin, SJ, Mackie, IJ, Muirhead, N, RAPS trial investigators, ., Ruiz-Castellano, M, Sylvestre, Y   +14 more
core   +1 more source

Neutrophil extracellular traps (NETs) : formation and implications [PDF]

, 2013
Neutrophils are cells of the immune system which freely circulate in blood vessels and are recruited to the inflammation sites when the human organism responds to microbial infections.
Rąpała-Kozik, Maria, Zawrotniak, Marcin   +1 more
core   +1 more source

Patients with DVT and primary antiphospholipid syndrome have worse obstetric outcomes than pregnant women with DVT and negative antiphospholipid antibodies: a retrospective cohort study

São Paulo Medical Journal
BACKGROUND: Pregnant women are at an increased risk of thromboembolism compared with non-pregnant women. Venous thrombosis is a manifestation of antiphospholipid syndrome (APS), an autoimmune thrombophilia associated with pregnancy morbidity. OBJECTIVES:
Priscila Guyt Rebelo, Marcela Ignacchiti Lacerda Ávila, Nilson Ramires de Jesús, Flávio Victor Signorelli, Evandro Mendes Klumb, Guilherme Ramires de Jesús   +5 more
doaj   +1 more source

PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins?

Bleeding, Thrombosis and Vascular Biology
Background and Aims: Plasma mixing test is a simple laboratory procedure, which is performed on samples from patients with coagulation screening tests prolonged (mainly the activated partial thromboplastin (APTT), but also the prothrombin time (PT) or ...
doaj   +1 more source

NEWLY DIAGNOSED HEREDITARY FACTOR V DEFICIENCY IN A PATIENT PRESENTING WITH DEEP VEIN THROMBOSIS: A Rare Case

Hematology, Transfusion and Cell Therapy
Objective: Factor V (FV) is a crucial regulator of hemostasis, functioning as both a procoagulant and an anticoagulant glycoprotein within the coagulation cascade. In plasma, FV exists as an inactive precursor, which is activated by thrombin or factor Xa
Songül Beskisiz Dönen, Vehbi Demircan, Abdullah Karakuş, Mehmet Orhan Ayyıldız   +3 more
doaj   +1 more source

Kehamilan Dengan Sindroma Antifosfolipid [PDF]

, 2016
Antiphospholipid antibody syndrome is disorder of coagulation characterize with vascular thrombosis associated with increase of antiphospholipid (aPL) antibody such as anticardiolipin (aCL) antibodies, lupus anticoagulant (LA), and anti-beta 2 ...
herlambang, H. (herlambang)
core  

PO78 | Acquired hemophilia A as a paraneoplastic syndrome: two cases report on a rare coexistence

Bleeding, Thrombosis and Vascular Biology
Background: Acquired hemophilia, meanwhile, is the most common acquired disease affecting clotting factors. Possible causes that have been empirically described include autoimmune disease (such as rheumatoid arthritis or systemic lupus erythematosus ...
doaj   +1 more source

ACQUIRED HEMOPHILIA A IN A 3-YEAR-OLD PEDIATRIC PATIENT: A CASE REPORT OF RARE AND POTENTIALLY FATAL BLEEDING DISORDER

Hematology, Transfusion and Cell Therapy
Introduction: Acquired hemophilia A (AHA) is a rare severe autoimmune bleeding disorder with significant morbidity and mortality mainly occurring in older adults (average age 75). The condition is extremely rare in children.
Z Alrajhi, LLE Souza, M Carcao
doaj   +1 more source