Results 81 to 90 of about 9,998 (163)

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, Volume 81, Issue 8, Page 2675-2712, August 2026.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, Volume 209, Issue 2, Page 420-431, August 2026.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, Volume 27, Issue 8, August 2026.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Clinical application of a modified platelet desialylation test for mechanistic characterization of platelet transfusion refractoriness

Transfusion, Volume 66, Issue 8, Page 1520-1535, August 2026.
Abstract Background Platelet transfusion refractoriness (PTR) is a major challenge in transfusion medicine and may result from both immune and non‐immune mechanisms. Although alloantibodies are well‐established contributors, Fc‐independent pathways such as platelet desialylation have emerged as alternative mechanisms of clearance.
Karen Ziza, Thamy Silva, Mateus Domentino, Marina Conrado, João Oliveira, Elyse Moritz, Akemi Chiba, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Langhi Dante, Carla Dinardo   +11 more
wiley   +1 more source

Idiopathic Acquired Hemophilia A With High-Titer Factor VIII Inhibitor in an Elderly Patient: A Case Report. [PDF]

Cureus
Morris A, Hassan A, Alnsour T, Shafi N, Gonzalez Espinosa P, Levitt M.   +5 more
europepmc   +1 more source

Case Report: Telitacicept in the treatment of systemic lupus erythematosus complicated by acquired hemophilia A. [PDF]

Front Immunol
Liu X, Li W.
europepmc   +1 more source

Case Report: Rare factor V inhibitor found in a patient with ulcerative colitis during latent tuberculosis infection. [PDF]

Front Med (Lausanne)
Wang Y, Li N, Li X, He J.
europepmc   +1 more source

Case Report: Differential diagnosis and clinical management of isolated prolonged activated partial thromboplastin time. [PDF]

Front Immunol
Liu L, Guo D.
europepmc   +1 more source

Acquired Hemophilia A (AHA) Associated With Malignancy and Antiphospholipid Antibodies: Two Case Reports With Distinct Etiologies. [PDF]

Cureus
Htun NL, Win HT, Abdullah MA, Khine Oo HK, Thottacherry DJ.   +4 more
europepmc   +1 more source

Antiphospholipid antibody formation during immune checkpoint inhibition in patients with cancer: a prospective cohort study. [PDF]

Res Pract Thromb Haemost
Strijdhorst A, Salet DM, Schoenaker JM, van der Vegte V, Seijkens TTP, van Laarhoven HWM, Urbanus RT, van Es N.   +7 more
europepmc   +1 more source