The involvement of T regulatory lymphocytes in a cohort of lupus nephritis patients: a pilot study [PDF]
, 2015 T regulator lymphocytes (Tregs) play a key role in the maintenance of immune tolerance and in the development of autoimmune diseases. Expression of Foxp3 is specific for Tregs, and can be used for the identification of these cells.
Afeltra, Antonella +8 more
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A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis
Frontiers in Immunology, 2021 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu +19 more
doaj +1 more source
Expanding the Role of Complement Therapies: The Case for Lupus Nephritis
Journal of Clinical Medicine, 2021 The complement system is an innate immune surveillance network that provides defense against microorganisms and clearance of immune complexes and cellular debris and bridges innate and adaptive immunity.
Nicholas L. Li, D. Birmingham, B. Rovin
semanticscholar +1 more source
Urinary CXCL10: a marker of nephritis in lupus patients
Reumatismo, 2014 Systemic lupus erythematosus (SLE) is a connective tissue disease characterized by the formation of autoantibodies and immune complexes. Lupus nephritis is one of the hallmark features of SLE.
M. A. Marie +2 more
doaj +1 more source
A lupus nephritis kezelésének irányelvei, valamint a mycofenolat mofetil hatékonyságának bemutatása intézetünk lupus nephritises betegeinek körében | Clinical guideline for the treatment of lupus nephritis and single-centre results of mycofenolate mofetil among patients with lupus nephritis in the National Institute of Rheumatology and Physiotherapy, Budapest [PDF]
, 2016 Absztrakt A szerzők közleményükben a lupus nephritis kezelésének legújabb irányelvei mellett bemutatják saját mycofenolat mofetillel szerzett tapasztalataikat a betegség kezelésében.
Kiss, Emese, Szabó, Melinda Zsuzsanna
core +1 more source
مجله دانشکده پزشکی اصفهان, 2019 Background: Concerning the importance and the high frequency of renal involvement in patients with systemic lupus erythematosus (SLE), and the ability to measure the value of hematuria on predicting the incidence of lupus nephritis, this study aimed to ...
Maryam Mousavi +2 more
doaj +1 more source
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis. [PDF]
PLoS ONE, 2010 BACKGROUND: Deposition of chromatin-IgG complexes within glomerular membranes is a key event in the pathogenesis of lupus nephritis. We recently reported an acquired loss of renal Dnase1 expression linked to transformation from mild to severe ...
Svetlana N Zykova +2 more
doaj +1 more source
A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis. [PDF]
, 2016 BackgroundManagement of lupus nephritis (LN) would be greatly aided by the discovery of biomarkers that accurately reflect changes in disease activity.
Avila-Casado, Carmen +10 more
core +3 more sources
Does Rheumatoid Factor have any Protective Role in Patients with Lupus Nephritis [PDF]
Al-Anbar Medical Journal, 2020 Background: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that appears to result from an immune-regulatory disturbance caused by an interplay of genetic, hormonal, immunological, and environmental factors.
Khamis Y. C. AL-Qubaeissy +3 more
doaj +1 more source
Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial. [PDF]
, 2019 BackgroundTreatment decision-making regarding immunosuppressive therapy is challenging for individuals with lupus. We assessed the effectiveness of a decision aid for immunosuppressive therapy in lupus nephritis.Methods and findingsIn a United States ...
Alarcón, Graciela S +27 more
core +2 more sources