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Update on Lupus Nephritis: Core Curriculum 2020.
American Journal of Kidney Diseases, 2020 Systemic lupus erythematosus is a multisystem autoimmune disease that commonly affects the kidneys. Lupus nephritis (LN) is the most common cause of kidney injury in systemic lupus erythematosus and a major risk factor for morbidity and mortality.
S. Parikh +3 more
semanticscholar +1 more source
Urinary CXCL10: a marker of nephritis in lupus patients
Reumatismo, 2014 Systemic lupus erythematosus (SLE) is a connective tissue disease characterized by the formation of autoantibodies and immune complexes. Lupus nephritis is one of the hallmark features of SLE.
M. A. Marie +2 more
doaj +1 more source
A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis
Frontiers in Immunology, 2021 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu +19 more
doaj +1 more source
Autoimmunity Reviews, 2021 Kidney involvement confers significant morbidity and mortality in patients with systemic lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse mechanisms instigated by elements of the autoimmune response which alter the ...
S. Jamaly +4 more
semanticscholar +1 more source
مجله دانشکده پزشکی اصفهان, 2019 Background: Concerning the importance and the high frequency of renal involvement in patients with systemic lupus erythematosus (SLE), and the ability to measure the value of hematuria on predicting the incidence of lupus nephritis, this study aimed to ...
Maryam Mousavi +2 more
doaj +1 more source
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis. [PDF]
PLoS ONE, 2010 BACKGROUND: Deposition of chromatin-IgG complexes within glomerular membranes is a key event in the pathogenesis of lupus nephritis. We recently reported an acquired loss of renal Dnase1 expression linked to transformation from mild to severe ...
Svetlana N Zykova +2 more
doaj +1 more source
Biomedicines, 2023 Lupus nephritis (LN) is one of the most common and serious complications of systemic lupus erythematosus (SLE). The risk factors for developing LN by SLE patients are not fully understood. They are considered to be a mix of genetic and environmental variables, one of them being dysbiosis, proposed recently to interfere with autoimmunity. As of yet, the
Marta Monticolo +2 more
openaire +3 more sources
Does Rheumatoid Factor have any Protective Role in Patients with Lupus Nephritis [PDF]
Al-Anbar Medical Journal, 2020 Background: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that appears to result from an immune-regulatory disturbance caused by an interplay of genetic, hormonal, immunological, and environmental factors.
Khamis Y. C. AL-Qubaeissy +3 more
doaj +1 more source
Lupus, 2020 Objective The understanding of systemic lupus erythematosus (SLE) and lupus nephritis (LN) pathogenesis remains incomplete. This review assessed LN development in SLE, within-LN progression and progression to end-stage renal disease (ESRD).
Anadi Mahajan +6 more
semanticscholar +1 more source
Mediators of Inflammation, 2023 Objective. Modified C-reactive protein (mCRP) is known to be involved in the upregulation and amplification of the local inflammatory response. This study investigated the circulating and local levels of mCRP and their relevance to clinicopathological ...
Mo Yuan +4 more
doaj +1 more source