Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis. [PDF]
PLoS ONE, 2013 Lupus nephritis is a cause of significant morbidity in systemic lupus erythematosus (SLE) and its genetic background has not been completely clarified.
Karin Bolin +11 more
doaj +1 more source
The involvement of T regulatory lymphocytes in a cohort of lupus nephritis patients: a pilot study [PDF]
, 2015 T regulator lymphocytes (Tregs) play a key role in the maintenance of immune tolerance and in the development of autoimmune diseases. Expression of Foxp3 is specific for Tregs, and can be used for the identification of these cells.
Afeltra, Antonella +8 more
core +1 more source
A lupus nephritis kezelésének irányelvei, valamint a mycofenolat mofetil hatékonyságának bemutatása intézetünk lupus nephritises betegeinek körében | Clinical guideline for the treatment of lupus nephritis and single-centre results of mycofenolate mofetil among patients with lupus nephritis in the National Institute of Rheumatology and Physiotherapy, Budapest [PDF]
, 2016 Absztrakt A szerzők közleményükben a lupus nephritis kezelésének legújabb irányelvei mellett bemutatják saját mycofenolat mofetillel szerzett tapasztalataikat a betegség kezelésében.
Kiss, Emese, Szabó, Melinda Zsuzsanna
core +1 more source
Urinary CXCL10: a marker of nephritis in lupus patients
Reumatismo, 2014 Systemic lupus erythematosus (SLE) is a connective tissue disease characterized by the formation of autoantibodies and immune complexes. Lupus nephritis is one of the hallmark features of SLE.
M. A. Marie +2 more
doaj +1 more source
A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis. [PDF]
, 2016 BackgroundManagement of lupus nephritis (LN) would be greatly aided by the discovery of biomarkers that accurately reflect changes in disease activity.
Avila-Casado, Carmen +10 more
core +3 more sources
A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis
Frontiers in Immunology, 2021 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu +19 more
doaj +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
مجله دانشکده پزشکی اصفهان, 2019 Background: Concerning the importance and the high frequency of renal involvement in patients with systemic lupus erythematosus (SLE), and the ability to measure the value of hematuria on predicting the incidence of lupus nephritis, this study aimed to ...
Maryam Mousavi +2 more
doaj +1 more source
Renal Dnase1 enzyme activity and protein expression is selectively shut down in murine and human membranoproliferative lupus nephritis. [PDF]
PLoS ONE, 2010 BACKGROUND: Deposition of chromatin-IgG complexes within glomerular membranes is a key event in the pathogenesis of lupus nephritis. We recently reported an acquired loss of renal Dnase1 expression linked to transformation from mild to severe ...
Svetlana N Zykova +2 more
doaj +1 more source
Pediatric lupus nephritis [PDF]
Brazilian Journal of Nephrology, 2019 Abstract Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates.
Sergio Veloso Brant Pinheiro +4 more
openaire +6 more sources