Results 11 to 20 of about 109,330 (215)

Mycophenolate mofetil in the treatment of lupus nephritis

Biologics: Targets & Therapy, 2008
Patrick FK Yong1,2, David P D’Cruz21Department of Clinical Immunology, Kings College Hospital; 2The Lupus Research Unit, St Thomas’ Hospital, London, UKAbstract: Lupus nephritis is a complication of systemic lupus erythematosus, which
Patrick FK Yong, David P D’Cruz   +1 more
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Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis

Lupus Science and Medicine, 2022
Objective Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus (SLE). Lupus nephritis is a major cause of kidney failure in patients with SLE, attributed to increased morbidity and mortality.
Samy Hakroush, Björn Tampe, Desiree Tampe   +2 more
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Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
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Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis. [PDF]

PLoS ONE, 2013
Lupus nephritis is a cause of significant morbidity in systemic lupus erythematosus (SLE) and its genetic background has not been completely clarified.
Karin Bolin, Johanna K Sandling, Agneta Zickert, Andreas Jönsen, Christopher Sjöwall, Elisabet Svenungsson, Anders A Bengtsson, Maija-Leena Eloranta, Lars Rönnblom, Ann-Christine Syvänen, Iva Gunnarsson, Gunnel Nordmark   +11 more
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The Role of Anti-mCRP Autoantibodies in Lupus Nephritis

Kidney Diseases, 2023
Background: Lupus nephritis is characterized by multiple autoantibodies production. However, there are few autoantibodies associated with disease activity and prognosis.
Mo Yuan, Ying Tan, Ming-hui Zhao
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Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
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Urinary CXCL10: a marker of nephritis in lupus patients

Reumatismo, 2014
Systemic lupus erythematosus (SLE) is a connective tissue disease characterized by the formation of autoantibodies and immune complexes. Lupus nephritis is one of the hallmark features of SLE.
M. A. Marie, R. E. Abu Khalil, H. M. Habib   +2 more
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Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin : an open-label dose escalation study [PDF]

, 2011
Introduction: As the immunosuppressive potency of 15-deoxyspergualin (DSG) has been shown in the therapy of renal transplant rejection and Wegener's granulomatosis, the intention of this study was to evaluate the safety of DSG in the therapy of lupus ...
Hauser, Ingeborg A., Tesar, Vladimir, Heinzel, Peter A., Hiepe, Falk, Peter A Heinzel, Wilhelm H Schmitt, Vladimir Tesar, Ulf Müller-Ladner, Woehling, Heike, Nemoto, Kyuichi, Heike Woehling, Hanns-Martin Lorenz, Müller-Ladner, Ulf, Kyuichi Nemoto, Falk Hiepe, Lorenz, Hanns-Martin, Tarner, Ingo, Ingo Tarner, Tobias Alexander, Schmitt, Wilhelm H., Ingeborg A Hauser, Alexander, Tobias   +21 more
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A Novel Autoantibody Induced by Bacterial Biofilm Conserved Components Aggravates Lupus Nephritis

Frontiers in Immunology, 2021
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with multiple autoantibody production and often affects the kidneys, known as lupus nephritis. However, the mechanism underlying lupus nephritis development is unclear.
Wenyan Fu, Wenyan Fu, Yu Liu, Yu Liu, Fangjie Liu, Fangjie Liu, Chenghua Liu, Chenghua Liu, Jingjing Li, Jiali Niu, Peng Han, Dan Xu, Jiaojiao Hou, Yuanfang Ma, Jiannan Feng, Jiannan Feng, Zhanguo Li, Rong Mu, Guang Yang, Guang Yang   +19 more
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The Frequency of Lupus Nephritis and Hematuria in Patients with Systemic Lupus Erythematous in Isfahan City, Iran

مجله دانشکده پزشکی اصفهان, 2019
Background: Concerning the importance and the high frequency of renal involvement in patients with systemic lupus erythematosus (SLE), and the ability to measure the value of hematuria on predicting the incidence of lupus nephritis, this study aimed to ...
Maryam Mousavi, Zahra Sayed-Bonakdar, Habibeh Mohammadi   +2 more
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