Results 11 to 20 of about 268,948 (265)
Nature Reviews Disease Primers, 2020 Lupus nephritis (LN) is a form of glomerulonephritis that constitutes one of the most severe organ manifestations of the autoimmune disease systemic lupus erythematosus (SLE). Most patients with SLE who develop LN do so within 5 years of an SLE diagnosis and, in many cases, LN is the presenting manifestation resulting in the diagnosis of SLE ...
Hans-Joachim Anders +2 more
exaly +8 more sources
Lupus Nephritis in Children: Novel Perspectives
Medicina, 2023 Childhood-onset systemic lupus erythematosus is an inflammatory and autoimmune condition characterized by heterogeneous multisystem involvement and a chronic course with unpredictable flares.
Marco Pennesi, Simone Benvenuto
doaj +2 more sources
Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis
JCI Insight, 2023 Lupus nephritis is a serious complication of systemic lupus erythematosus, mediated by IgG immune complex (IC) deposition in kidneys, with limited treatment options. Kidney macrophages are critical tissue sentinels that express IgG-binding Fcγ receptors (
Nathan Richoz +14 more
doaj +2 more sources
Evaluation of Urinary Ceruloplasmin as a Novel Biomarker for Lupus Nephritis [PDF]
Al-Azhar International Medical Journal, 2023 Background: A crucial step in modifying the course of lupus nephritis is the early identification of kidney disease in systemic lupus patients. Lupus nephritis affects around 30% to 60% of SLE patients and 70% of juvenile SLE.
Muhammad Harb +3 more
doaj +1 more source
A study on the relationship between morphological lesions of lupus nephritis with demographic and biochemical findings [PDF]
Journal of Preventive Epidemiology, 2022 Introduction: Lupus nephritis is one of the important aspects of systemic lupus erythematosus (SLE). Objectives: This study aimed to investigate possible relationship between pathological lesions of lupus nephritis classes and demographic and biochemical
Nasrin Tavassoli +2 more
doaj +1 more source
Increase in direct costs for health systems due to lupus nephritis: the case of Colombia
Einstein (São Paulo), 2022 Objective Lupus nephritis is one of the most severe complications of systemic lupus erythematosus and it has been estimated that can occur in up to 60% of patients. Direct costs of lupus nephritis have not been studied in developing countries.
Sergio I Prada +3 more
doaj +1 more source
Arthritis & Rheumatology, 2023 AURORA 2 evaluated the long‐term safety, tolerability, and efficacy of voclosporin compared to placebo in patients with lupus nephritis (LN) receiving an additional two years of treatment following completion of the one‐year AURORA 1 study.
Amit Saxena +17 more
semanticscholar +1 more source
Novel Therapeutics for Management of Lupus Nephritis: What Is Next?
Kidney Medicine, 2023 Lupus nephritis is a severe, organ-threatening manifestation of systemic lupus erythematosus. The current standard of care in the treatment of lupus nephritis is limited to broad-spectrum immunosuppressants, which have significant concerns of short- and ...
Sayali B. Thakare +5 more
doaj +1 more source
Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA. [PDF]
PLoS ONE, 2013 Lupus nephritis is one of the most serious manifestations and one of the strongest predictors of a poor outcome in systemic lupus erythematosus (SLE).
Zhenke Wen +5 more
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RMD Open, 2022 Lupus nephritis is one of the most common and serious complications of systemic lupus erythematosus, attributed to increased morbidity and mortality. The in situ deposition of intrarenal immune complexes promote the accumulation of inflammatory cells and
Samy Hakroush +2 more
doaj +1 more source