Results 21 to 30 of about 65,459 (255)
Does Rheumatoid Factor have any Protective Role in Patients with Lupus Nephritis [PDF]
Al-Anbar Medical Journal, 2020 Background: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that appears to result from an immune-regulatory disturbance caused by an interplay of genetic, hormonal, immunological, and environmental factors.
Khamis Y. C. AL-Qubaeissy +3 more
doaj +1 more source
Prophylactic inhibition of soluble epoxide hydrolase delays onset of nephritis and ameliorates kidney damage in NZB/W F1 mice [PDF]
, 2019 Epoxy-fatty-acids (EpFAs), cytochrome P450 dependent arachidonic acid derivatives, have been suggested to have anti-inflammatory properties, though their effects on autoimmune diseases like systemic lupus erythematosus (SLE) have yet to be investigated ...
Dragun, Duska +9 more
core +2 more sources
Anti-dsDNA negative and anti-Ro positive lupus nephritis: a report of a rare case
Reumatismo, 2014 Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease, characterized by an autoantibody response to various nuclear and cytoplasmic antigens.
D. Jain +5 more
doaj +1 more source
Mediators of Inflammation, 2023 Objective. Modified C-reactive protein (mCRP) is known to be involved in the upregulation and amplification of the local inflammatory response. This study investigated the circulating and local levels of mCRP and their relevance to clinicopathological ...
Mo Yuan +4 more
doaj +1 more source
Non-Coding RNA, 2023 Long non-coding RNA (lncRNA) TUG1 acts as a proto-oncogene, allowing the proliferation of tumor cells, and it has been related to inflammation. Therefore, we aimed in this study to investigate for the first time the role of TUG1 gene polymorphism and the
Gehan Abd-Elfatah Tawfeek +6 more
doaj +1 more source
SERPINB3 delays glomerulonephritis and attenuates the lupus-like disease in lupus murine models by inducing a more tolerogenic immune phenotype [PDF]
, 2018 Objective: To explore the effects of SERPINB3 administration in murine lupus models with a focus on lupus-like nephritis. Methods: 40 NZB/W F1 mice were subdivided into 4 groups and intraperitoneally injected with recombinant SERPINB3 (7.5 \u3bcg/0.1 mL ...
Beggio, M +12 more
core +2 more sources
Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis
JCI Insight, 2023 Lupus nephritis is a serious complication of systemic lupus erythematosus, mediated by IgG immune complex (IC) deposition in kidneys, with limited treatment options. Kidney macrophages are critical tissue sentinels that express IgG-binding Fcγ receptors (
Nathan Richoz +14 more
doaj +1 more source
Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]
, 2003 To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim +5 more
core +1 more source
Tubulointerstitial lupus nephritis [PDF]
Journal of Nephropathology, 2013 Isolated or predominant tubulointerstitial lupus nephritis is rare.Here we report the case of a thirty eight years old male who was diagnosed with systemic lupus erythematosus (SLE) according to clinical and laboratory criteria and presented with impaired renal function and non nephrotic range proteinuria.
Ala Ali, Souad Al-Windawi
openaire +3 more sources
Rheumatology & Autoimmunity, 2023 Background Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by development of autoantibodies and multiorgan involvement. Kidney involvement, termed lupus nephritis, has major impact on life expectancy.
Yi Tong V. Aw +14 more
doaj +1 more source