Results 141 to 150 of about 108,236 (258)

Ion binding sites and intermediate domain closure induced by D‐serine in the GluD1 ligand‐binding domain

The FEBS Journal, EarlyView.
GluD1 belongs to the ionotropic glutamate receptors and has important functions in the brain and brain diseases. We report the crystal structure of the GluD1 ligand‐binding domain with D‐serine and zinc ions. MD simulations supported promiscuous binding of cations and that chloride ions play a stabilizing role. Pro725 seems to hinder interlobe closure,
Flemming Steen Jørgensen, Emma Grosvald Pedersen, Dilip Narayanan, Karla A. Frydenvang, Jette Sandholm Kastrup   +4 more
wiley   +1 more source

Organic Polyurethane Surface Structures to Manufacture Noneluting Antimicrobial Polyurethanes: A Systematic Review of Literature. [PDF]

Biomed Res Int
Hurck BJ, Vargas Guerrero MG, de Boer C, Dias AA, Arts JJC.   +4 more
europepmc   +1 more source

Single‐Cell Atlas Reveals Neutrophil Heterogeneity in Hypervirulent Klebsiella pneumoniae Infection‐Induced Sepsis

Immunology, EarlyView.
The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang, Weizhao Li, Xinyu Zhang, Sohana Akter Mina, Qianling Jiang, Gaochen Zhu, Sheng Chen, Guan Yang   +7 more
wiley   +1 more source

Draft genome sequence of a KPC-2-producing, meropenem-durlobactam non-susceptible <i>Klebsiella pneumoniae</i> ST11-KL64 clinical isolate. [PDF]

Microbiol Resour Announc
Wen H, Feng Y, Zong Z.
europepmc   +1 more source

Enrichment‐Based Duplex PCR for Early Detection of Potentially Virulent Vibrio harveyi in Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Vibrio harveyi is an important bacterial pathogen in marine aquaculture, responsible for outbreaks affecting a wide range of fish species. Early detection of potentially virulent isolates in fish and environmental samples is essential for effective disease prevention and management, particularly under field conditions where the pathogen may be
Javier Barriga‐Cuartero, Carla Hernández‐Cabanyero, Pablo Ibanyez‐Paya, Carmen Amaro, Belen Fouz   +4 more
wiley   +1 more source

Impact of pulmonary hypertension on atrial fibrillation recurrence after pulmonary vein isolation: A prospective multicenter registry study. [PDF]

Int J Cardiol Heart Vasc
Massalha E, Dakka A, Marai I, Michowitz Y, Glikson M, Konstantino Y, Haim M, Luria D, Omelchenko A, Laish-Farkash A, Suleiman M, Furer A, Nof E, Beinart R, Israeli Working Group on Pacing Electrophysiology.   +14 more
europepmc   +1 more source

Do Women Executives Make Workplaces Safer? Evidence from Workplace Safety Violations

Journal of Management Studies, EarlyView.
Abstract In this study, we develop and test theory on whether, when, and how the prevalence of women in firms’ top management influences workplace safety – an important ‘do no harm’ dimension of corporate social performance. Consistent with our theorizing, we find that there is a negative relationship between the prevalence of women executives in firms’
Yangyang Chen, Emmanuel Ofosu, Don O’Sullivan, Shi Tang, Leon Zolotoy   +4 more
wiley   +1 more source

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

Molecular Microbiology, EarlyView.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun, Gracious Y. Donkor, Julius K. Narh, Grady D. Jacobson, Cade Ward, Patrick O. Tawiah, Lisa K. Polzer, Kevin A. Edwards, Kyle A. Floyd, Jan‐Ulrik Dahl   +9 more
wiley   +1 more source

Generalized Galton's boards explain social phenomena via statistical physics. [PDF]

Sci Rep
Auricchio G, Ghiotto M, Gualandi S, Toscani G.   +3 more
europepmc   +1 more source

Knowledge and Argument

Noûs, EarlyView.
ABSTRACT I argue that knowledge plays a distinctive role in psychological explanation that weaker epistemic states cannot because it is robust in the face of counterevidence in a way that they are not. Being robust in the face of counterevidence makes your belief robust in the face of counterargument.
Spencer Paulson
wiley   +1 more source