Results 1 to 10 of about 206,376 (396)
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Nature Communications, 2020 Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage
Jeroen Baardman +2 more
exaly +2 more sources
Journal of Lipid Research, 2020 Sphingosine 1-phosphate (S1P) lyase is an intracellular enzyme that catalyzes the irreversible degradation of S1P and has been suggested as a therapeutic target for the treatment of psoriasis vulgaris. Because S1P induces differentiation of keratinocytes,
Suwon Jeon +9 more
doaj +2 more sources
ATP citrate lyase is increased in human breast cancer, depletion of which promotes apoptosis
Tumor Biology, 2017 Breast cancer is a malignant tumor that is harmful to women’s health around the world. Investigating the biological mechanism is, therefore, of pivotal importance to improve patients’ prognoses.
Diyu Wang +4 more
doaj +2 more sources
Acetyl-CoA-mediated activation of Mycobacterium tuberculosis isocitrate lyase 2
Nature Communications, 2019 Isocitrate lyase (ICL) isoforms 1 and 2 are enzymes in the glyoxylate and methylcitrate cycles that enable Mycobacterium tuberculosis (Mtb) to use lipids as a carbon source.
Ram Prasad Bhusal +7 more
doaj +2 more sources
Screening of alginate lyase-excreting microorganisms from the surface of brown algae
AMB Express, 2017 Alginate lyase is a biocatalyst that degrades alginate to produce oligosaccharides, which have many bioactive functions and could be used as renewable biofuels.
Mingpeng Wang +5 more
doaj +2 more sources
Research progress on Streptococcus mutans phages in the prevention of dental caries
口腔疾病防治, 2021 The Streptococcus mutans (S. mutans) phage, as one of the principal pathogenic bacteria of dental caries, is a main cause of the formation and development of dental caries due to its overproliferation in dental plaque biofilms.
LI Yuhan +5 more
doaj +1 more source
Пищевые системы, 2023 Special features of the protopectin complex structure of plant tissue suggest the necessity of performing point destruction of certain glycoside bonds in the structure of rhamnogalacturonan polymer chains for industrial production of pectin. These chains
V. V. Kondratenko, T. Yu. Kondratenko
doaj +1 more source
Marine Drugs, 2022 Alginate oligosaccharides (AOS) have many biological activities and significant applications in prebiotics, nutritional supplements, and plant growth development. Alginate lyases have unique advantages in the preparation of AOS.
Z. Xue +7 more
semanticscholar +1 more source
Investigation of the Molecular Mechanisms of the Eukaryotic Cytochrome-c Maturation System
Biomolecules, 2022 Cytochromes-c are ubiquitous heme proteins with enormous impact at the cellular level, being key players in metabolic processes such as electron transfer chains and apoptosis.
Ana V. Silva +4 more
doaj +1 more source
Molecules, 2022 In this study, we aimed to isolate bacteria capable of degrading the polysaccharide ulvan from the green algae Ulva sp. (Chlorophyta, Ulvales, Ulvaceae) in marine environments.
Reiji Tanaka +3 more
doaj +1 more source