Results 161 to 170 of about 3,343 (218)

Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum. [PDF]

Plant Biotechnol J
Lamichhane B, Gélinas SE, Merindol N, Koirala M, Dos Santos KCG, Germain H, Desgagné-Penix I.   +6 more
europepmc   +1 more source

Narciclasine as a potential therapeutic agent to overcome EGFR-TKI resistance in non-small cell lung cancer. [PDF]

J Transl Med
Sung JY, Yoo HE, Kim S, Yu S, Park SW, Lim GE, Lee BI, Yoon K, Kim HJ, Ye SK, Shim J, Kim YN.   +11 more
europepmc   +1 more source

Plant Alkaloids as Promising Anticancer Compounds with Blood-Brain Barrier Penetration in the Treatment of Glioblastoma: In Vitro and In Vivo Models. [PDF]

Molecules
Ożarowski M, Karpiński TM, Czerny B, Kamiński A, Seremak-Mrozikiewicz A.   +4 more
europepmc   +1 more source

<i>Lycorine hydrochloride</i> Suppresses the Proliferation and Invasion of Esophageal Cancer by Targeting TRIM22 and Inhibiting the JAK2/STAT3 and Erk Pathways. [PDF]

Cancers (Basel)
Liu J, Qiu L, Chen J, Zeng T.
europepmc   +1 more source

Direct somatic embryogenesis, genetic fidelity assessment and GC-MS analysis of regenerated Crinum asiaticum L. Plants. [PDF]

BMC Plant Biol
Bansal Y, Mujib A, Mamgain J, Grover S, Dewir YH, Székely Á.   +5 more
europepmc   +1 more source

Lycorine effective against Yellow Fever Virus

, 2015
openaire   +1 more source

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GC–MS of some lycorine‐type Amaryllidaceae alkaloids

Journal of Mass Spectrometry, 2021
AbstractThe search for novel bioactive compounds and the identification of known ones in the plant kingdom are a challenge for the scientists working in different fields of plant science. In the recent years, mass spectrometry is the most frequently applied method for analysis of complex mixtures of plant metabolites.
Strahil Berkov, Laura Torras‐Claveria, Francesc Viladomat, Sergio Suárez, Jaume Bastida   +4 more
openaire   +2 more sources

Lycorine alkaloids from Hymenocallis littoralis

Phytochemistry, 1995
From Hymenocallis littoralis, one new alkaloid, named littoraline, together with 13 known lycorine alkaloids and one lignan, were isolated. The structure and NMR assignments of this new alkaloid were determined by 1D and 2D NMR techniques. Littoraline showed inhibitory activity of HIV reverse transcriptase, and lycorine and haemanthamine showed potent ...
L Z, Lin, S F, Hu, H B, Chai, T, Pengsuparp, J M, Pezzuto, G A, Cordell, N, Ruangrungsi   +6 more
openaire   +2 more sources

Lycorine structure-activity relationships

Phytochemistry, 1983
Abstract Twenty three lycorine derivatives and naturally occurring alkaloids, structurally related to lycorine, were tested for their ability to inhibit ascorbic acid biosynthesis in potato tubers. The following relationships between structure modification and activity were observed: (a) cleavage of the acetalic bonds on the dioxole ring had no ...
EVIDENTE, ANTONIO, Maria Rosaria Cicala, Giacomino Randazzo, Rodolfo Riccio, Giuseppe Calabrese, Rosalia Liso, Oreste Arrigoni   +6 more
openaire   +2 more sources

Synthesis and antiviral activity of lycorine derivatives

Journal of Asian Natural Products Research, 2020
There are no effective antiviral drugs to treat hand, foot, and mouth disease. In this study, a series of lycorine derivatives were synthesized and evaluated against enterovirus 71 and coxsackievirus A16 in vitro. Derivatives 7c-m with the phenoxyacyl group at the C-1 position showed higher efficacy and lower toxicity than lycorine.
Ya-Jun, Yang, Jiang-Ning, Liu, Xian-Dao, Pan   +2 more
openaire   +2 more sources