Results 41 to 50 of about 14,147 (202)

An Enzyme-Linked Immunosorbent Spot Assay Measuring Borrelia burgdorferi B31-Specific Interferon Gamma-Secreting T Cells Cannot Discriminate Active Lyme Neuroborreliosis from Past Lyme Borreliosis: a Prospective Study in the Netherlands. [PDF]

, 2018
Two-tier serology testing is most frequently used for the diagnosis of Lyme borreliosis (LB); however, a positive result is no proof of active disease. To establish a diagnosis of active LB, better diagnostics are needed. Tests investigating the cellular
Bossink, A W J, Bouwman, J J M, Ismail, D M, Kremer, K, Muilwijk, R H, Notermans, D W, Salomons, M, Sankatsing, S U C, Thijsen, S F T, van Gorkom, T, Vlaminckx, B J M, Voet, W   +11 more
core   +1 more source

HEMATOLOGICAL PARAMETERS IN PREDICTING OF THE COURSE OF LYME BORRELIOSIS IN CHILDREN

Детские инфекции (Москва), 2015
The study involved 224 patients with Lyme borreliosis children with erythema (103) and without erythema (121 children) forms. The analysis of the clinical symptoms and hematological parameters in the course of the disease was prosecute.
A. P. Pomogaeva, O. V. Obidina, M. O. Karavaeva   +2 more
doaj   +1 more source

Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis [PDF]

, 2015
Objectives: Prompt antibiotic treatment of early stage Lyme borreliosis (LB) prevents progression to severe multisystem disease. There is a clinical need to improve the diagnostic specificity of early stage Lyme assays in the period prior to the mounting
Alessandra Luchini, Benjamin H. Espina, Benjamin Lepene, Christine Mayuga, Donald M. Poretz, Emanuel F. III Petricoin, Gilbert R. Irwin, Ketul Shah, Lance A. Liotta, Mary Frekko Kilavos, Ross Dunlap, Ruben Magni, Sally Rucker, Samuel M. Shor, Temple A. Douglas, Virginia Espina   +15 more
core   +3 more sources

Ability to cause erythema migrans differs between Borrelia burgdorferi sensu lato isolates [PDF]

, 2013
Background: Lyme borreliosis is a tick-borne disease caused by Borrelia burgdorferi sensu lato. The variety of characteristic and non-specific clinical manifestations is partially explained by its genetic diversity.
Hengeveld, P. (Paul), Koopmans D.V.M., M.P.G. (Marion), Pandak, N. (Nenad), Sprong, H. (Hein), Takumi, K. (Katsuhisa), Tijsse-Klasen, E. (Ellen)   +5 more
core   +4 more sources

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

HEMOGRAM INDICATORS ASSESSMENT FOR EARLY PREDICTING THE MIXED INFECTION OF THE ERYTHEMA MIGRANS FORM OF LYME BORRELIOSIS AND TICK-BORNE ENCEPHALITIS

Siberian Journal of Life Sciences and Agriculture, 2023
Background. It is difficult to confirm the diagnosis of the mixed infection of the erythema migrans form of Lyme borreliosis and tick-borne encephalitis at the onset of the disease because of delayed seroconversion. Purpose.
Ekaterina N. Ilyinskikh, Evgenia N. Filatova, Alina V. Reshetova   +2 more
doaj   +1 more source

Therapy of lyme disease [PDF]

, 2016
Borrelia burgdorferi is highly susceptible to antibiotic treatment and the majority of patients profit from this treatment. Antibiotic selection, dose and route of administration, and duration of therapy for Lyme disease depend on the patient\u2019s ...
di Meo, Nicola, Errichetti, Enzo, Nan, Katiuscia, Pinzani, Caterina, Stinco, Giuseppe, Trevisan, Giusto   +5 more
core   +1 more source

Urgent natural foci infections transmitted by ticks in Saint-Petersburg

Журнал инфектологии, 2018
Purpose: to conduct a comparative analysis and to identify the epidemiological and clinical features of tick-borne encephalitis (TBE) and Lyme borreliosis as a mono- and coinfections in St. Petersburg. Materials and methods.
V. V. Nechaev, A. A. Yakovlev, A. N. Uskov, L. E. Boburina, N. V. Lavrova, M. N. Pogromskaya, B. I. Aslanov, A. O. Shapar, S. V. Pavlenko, L. N. Pozhidaeva, A. K. Ivanov, A. I. Kravtsova, S. A. Leppik, E. I. Vitovich, M. I. Fedunyak   +14 more
doaj   +1 more source

Ocular Lyme Borreliosis

American Journal of Ophthalmology, 1989
In six patients with ocular Lyme borreliosis, bilateral granulomatous iridocyclitis and vitritis were present in five. One of these five also had bilateral optic neuritis. Another patient developed combined trochlear and facial nerve palsies. A syndrome resembling pars planitis with atypical features such as granulomatous keratic precipitates and ...
K E, Winward, J L, Smith, W W, Culbertson, A, Paris-Hamelin   +3 more
openaire   +2 more sources

Borrelia Infections Under B Cell‐Depleting Therapies: A Systematic Review of Diagnostic Challenges and Outcomes With Special Focus on Neurological Forms

European Journal of Neurology, Volume 33, Issue 1, January 2026.
Neurological infections caused by Borrelia burgdorferi sensu lato and Borrelia miyamotoi are increasingly reported in patients receiving anti‐CD20 therapies and should be considered in cases presenting with neurological symptoms and cerebrospinal fluid pleocytosis.
Emilie Cardot‐Martin, Jean Baptiste Chanson, Cédric Lenormand, Pierre Boyer, Yves Hansmann, Jean Sibilia, Benoit Jaulhac, Marc Scherlinger   +7 more
wiley   +1 more source