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Aberrant T-cell phenotypes in a cohort of patients with post-treatment Lyme disease [PDF]
Frontiers in ImmunologyPost-treatment Lyme Disease (PTLD) is a poorly understood complication of Borrelia burgdorferi infection with significant patient morbidity. Characterized by fatigue, generalized myalgias, and cognitive impairment, PTLD symptomatology closely resembles ...
Alexander A. Girgis +13 more
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Lyme Disease Biobank: 10 years of 3 month follow-up visits from 2014 to 2023 [PDF]
Frontiers in MedicineIntroductionLyme Disease Biobank (LDB) enrolls participants with signs and symptoms of early Lyme disease (LD) from endemic areas and makes samples available to researchers developing more accurate diagnostics. From 2014 to 23, 466 cases and 367 controls
Elizabeth J. Horn +7 more
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Microorganisms, 2023 Breast cancer is one of the leading causes of death in women worldwide. Recent studies have demonstrated that inflammation due to infections with microorganisms could play a role in breast cancer development.
Ananya Debbarma +4 more
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Effect of Invasion of Borrelia burgdorferi in Normal and Neoplastic Mammary Epithelial Cells
Antibiotics, 2021 Borrelia burgdorferi, the causative agent of Lyme Disease, is known to be able to disseminate and colonize various organs and tissues of its hosts, which is very crucial for its pathogenicity and survival.
Gauri Gaur +6 more
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PLoS ONE, 2021 BackgroundLyme carditis, defined as direct infection of cardiac tissue by Borrelia bacteria, affects up to 10% of patients with Lyme disease. The most frequently reported clinical manifestation of Lyme carditis is cardiac conduction system disease.
Uwajachukwumma A Uzomah +9 more
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Lyme Disease in the Era of COVID-19: A Delayed Diagnosis and Risk for Complications
Case Reports in Infectious Diseases, 2021 We describe a patient with fever and myalgia who did not have COVID-19 but instead had Lyme disease. We propose that the co-occurrence of COVID-19 and Lyme disease during the spring of 2020 resulted in a delayed diagnosis of Lyme disease due to COVID-19 ...
Cheryl B. Novak +2 more
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The Platelet Fraction Is a Novel Reservoir to Detect Lyme Borrelia in Blood
Biology, 2020 Serological diagnosis of Lyme disease suffers from considerable limitations. Yet, the technique cannot currently be replaced by direct detection methods, such as bacterial culture or molecular analysis, due to their inadequate sensitivity.
Victoria P. Sanderson +4 more
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Outpatient visits before and after Lyme disease diagnosis in a Maryland employer-based health plan
BMC Health Services Research, 2023 Background Insurance claims data have been used to inform an understanding of Lyme disease epidemiology and cost of care, however few such studies have incorporated post-treatment symptoms following diagnosis.
Alison W. Rebman +6 more
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A diagnostic classifier for gene expression-based identification of early Lyme disease
Communications Medicine, 2022 Servellita et al. develop a machine learning-based classifier to diagnose Lyme disease using gene expression data. The classifier achieves high sensitivity for early infections, even prior to positivity on antibody testing.
Venice Servellita +13 more
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The utility of “Google Trends” for epidemiological research: Lyme disease as an example
Geospatial Health, 2010 Internet search engines have become an increasingly popular resource for accessing health-related information. The key words used as well as the number and geographic location of searches can provide trend data, as have recently been made available by ...
Ari Seifter +3 more
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