Results 1 to 10 of about 36,725 (131)
New England Journal of Medicine, 1989 Within the last decade, Lyme borreliosis has emerged as a complex new infection whose distribution is worldwide. The disorder is caused by a recently recognized spirochete, B. burgdorferi, transmitted by ticks of the I. ricinus complex. Certain species of mice are critical in the life cycle of the spirochete, and deer appear to be crucial to the tick ...
Allen Steere
exaly +15 more sources
A cofactor-promiscuous HMGR from the Lyme disease pathogen illuminates diversity in bacterial isoprenoid biosynthesis. [PDF]
Protein SciAbstract The Lyme disease pathogen Borrelia burgdorferi contains a highly reduced genome lacking many primary metabolic pathways. However, B. burgdorferi retains the mevalonate pathway that synthesizes isopentenyl pyrophosphate (IPP), the precursor to the peptidoglycan carrier lipid.
Paddy IA +7 more
europepmc +2 more sources
Lyme disease (Lyme borreliosis) [PDF]
FEMS Immunology and Medical Microbiology, 1997 Lyme disease (Lyme borreliosis) has become the most common tick-borne disease in the northern hemisphere. Lyme disease was first described in 1977 by Steere et al. [1]. The town, Old Lyme, CT, USA, was the initial focus of an unusual cluster of juvenile rheumatoid arthritis.
Toshiyuki Masuzawa +1 more
exaly +4 more sources
Current Opinion in Pediatrics, 1990 We now have more than 30 years of solid, scientific research about Lyme disease, a relatively common, vector-borne illness in parts of the United States and of Europe. Although there is still widespread misunderstanding of and misinformation about the disease among the lay public, its clinical manifestations as well as how to diagnose and to treat it ...
Dale R, Hamilton, John W, Bachman
+13 more sources
Clinics in Laboratory Medicine, 2010 Lyme disease, caused by the spirochete Borrelia burgdorferi, is the most common vector-borne disease in the United States. The clinical presentation varies depending on the stage of the illness: early disease includes erthyma migrans, early disseminated disease includes multiple erythema migrans, meningitis, cranial nerve palsies, and carditis; late ...
Thomas S, Murray, Eugene D, Shapiro
openaire +2 more sources
Clinical Infectious Diseases, 2000 Lyme disease, which is caused by Borrelia burgdorferi and transmitted in the United States primarily by Ixodes scapularis (the deer tick), is the most common vector borne disease in the United States. Its most frequent manifestation, a characteristic, expanding annular rash (erythema migrans), sometimes accompanied by myalgia, arthralgia, and malaise ...
E D, Shapiro, M A, Gerber
openaire +2 more sources
Eagle's Syndrome Presenting With Peripheral Facial Palsy—A Case Report
Head &Neck, EarlyView.ABSTRACT Background Eagle's syndrome is a condition caused by an elongated styloid process and is characterized by various symptoms such as cervicofacial pain, foreign body sensation, headache, odynophagia, and otalgia. However, the occurrence of a unilateral peripheral facial palsy as a symptom of Eagle's syndrome has been described only rarely ...
Vincent Holtmann +3 more
wiley +1 more source
Journal of Ultrasound in Medicine, EarlyView.This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan +3 more
wiley +1 more source
Bilateral Ophthalmoplegia After Neoadjuvant Pembrolizumab for Oral Cavity Squamous Cell Carcinoma
The Laryngoscope, EarlyView.The role of immune checkpoint inhibition (ICI) therapy in the treatment of head and neck squamous cell carcinoma (HNSCC) is expanding with increased utilization of neoadjuvant and adjuvant pembrolizumab in the setting of locally advanced disease. This report describes the presentation and management of the first known case of pembrolizumab‐induced ...
Leonard E. Estephan +3 more
wiley +1 more source
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims People living with amyotrophic lateral sclerosis (ALS; pALS) have extensive care needs, from wheelchairs to feeding tubes to caregiving support. The financial impact of these needs on pALS and their caregivers (cALS) has not been fully explored.
Astrid Grouls +5 more
wiley +1 more source