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Lyme Disease

New England Journal of Medicine, 1989
Within the last decade, Lyme borreliosis has emerged as a complex new infection whose distribution is worldwide. The disorder is caused by a recently recognized spirochete, B. burgdorferi, transmitted by ticks of the I. ricinus complex. Certain species of mice are critical in the life cycle of the spirochete, and deer appear to be crucial to the tick ...
Allen Steere, Steere Allen C
exaly   +15 more sources

A selective antibiotic for Lyme disease

Cell, 2021
Summary Lyme disease is on the rise. Caused by a spirochete Borreliella burgdorferi, it affects an estimated 500,000 people in the US alone. The antibiotics currently used to treat Lyme disease are broad-spectrum, damage the microbiome and select for ...
Helen Zgurskaya, Yu Imai, Kim Lewis
exaly   +2 more sources

Evaluation of standard and modified two-tiered testing algorithms using well-characterized early Lyme disease samples [PDF]

Journal of Clinical Microbiology
Current laboratory testing for Lyme disease (LD) relies on serology. We evaluated the performance of standard two-tiered testing (STTT) and modified two-tiered testing (MTTT) algorithms using samples obtained from well-characterized patients with early ...
Elizabeth J. Horn, Barry Menefee, Anna M. Schotthoefer, George Dempsey, Matt McArdle, Allison F. Weber, Cathy De Luca, Bobbi S. Pritt, John A. Branda   +8 more
doaj   +2 more sources

Pilot study of psilocybin in patients with post-treatment lyme disease [PDF]

Scientific Reports
Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common vector-borne disease in the United States and Europe. Although antibiotics effectively treat most cases, an estimated 10–20% of patients develop post-treatment Lyme disease ...
Albert Garcia-Romeu, Gideon P. Naudé, Alison W. Rebman, Sara So, Abigail Yaffe, Ian Geithner, Erica A. Kozero, Ting Yang, Mark J. Soloski, John N. Aucott   +9 more
doaj   +2 more sources

Lyme disease (Lyme borreliosis) [PDF]

FEMS Immunology and Medical Microbiology, 1997
Lyme disease (Lyme borreliosis) has become the most common tick-borne disease in the northern hemisphere. Lyme disease was first described in 1977 by Steere et al. [1]. The town, Old Lyme, CT, USA, was the initial focus of an unusual cluster of juvenile rheumatoid arthritis.
Y Yanagihara, Masuzawa Toshiyuki, Yasutake Yanagihara   +2 more
exaly   +3 more sources

What is the real number of Lyme disease cases in Canada?

BMC Public Health, 2019
Background Lyme disease is emerging in Canada due to expansion of the range of the tick vector Ixodes scapularis from the United States. National surveillance for human Lyme disease cases began in Canada in 2009.
N. H. Ogden, C. Bouchard, J. Badcock, M. A. Drebot, S. P. Elias, T. F. Hatchette, J. K. Koffi, P. A. Leighton, L. R. Lindsay, C. B. Lubelczyk, A. S. Peregrine, R. P. Smith, D. Webster   +12 more
doaj   +2 more sources

Chronic Lyme Disease: An Evidence-Based Definition by the ILADS Working Group

Antibiotics, 2019
Objective: Chronic Lyme disease has been a poorly defined term and often dismissed as a fictitious entity. In this paper, the International Lyme and Associated Diseases Society (ILADS) provides its evidence-based definition of chronic Lyme disease ...
Robert Bransfield, Elizabeth Maloney
exaly   +2 more sources

Health care costs, utilization and patterns of care following Lyme disease.

PLoS ONE, 2015
BackgroundLyme disease is the most frequently reported vector borne infection in the United States. The Centers for Disease Control have estimated that approximately 10% to 20% of individuals may experience Post-Treatment Lyme Disease Syndrome - a set of
Emily R Adrion, John Aucott, Klaus W Lemke, Jonathan P Weiner   +3 more
doaj   +2 more sources

Lyme Disease [PDF]

Current Opinion in Pediatrics, 1990
We now have more than 30 years of solid, scientific research about Lyme disease, a relatively common, vector-borne illness in parts of the United States and of Europe. Although there is still widespread misunderstanding of and misinformation about the disease among the lay public, its clinical manifestations as well as how to diagnose and to treat it ...
Dale R, Hamilton, John W, Bachman
  +13 more sources

Estimating the Frequency of Lyme Disease Diagnoses, United States, 2010–2018

Emerging Infectious Diseases, 2021
By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated in ≈476,000 patients in the United States annually during 2010–2018. Our results underscore the need for accurate diagnosis and improved prevention.
K. Kugeler, Amy M Schwartz, M. Delorey, P. Mead, A. Hinckley   +4 more
semanticscholar   +1 more source