Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
, 2016 Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
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Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs. [PDF]
, 2019 BackgroundRapidly progressive glomerulonephritis has been described in dogs that seroreact to Borrelia burgdorferi, but no studies have compared clinicopathologic differences in Lyme-seroreactive dogs with protein-losing nephropathy (PLN) versus dogs ...
Goldstein RE +6 more
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Journal of Clinical MicrobiologyThere are nearly 500,000 cases of Lyme disease each year in the United States; 10%–20% of them result in the development of a debilitating chronic disease known as post-treatment Lyme disease.
Anna F. Hickman +3 more
doaj +1 more source
, 2016 Borrelia burgdorferi is highly susceptible to antibiotic treatment and the majority of patients profit from this treatment. Antibiotic selection, dose and route of administration, and duration of therapy for Lyme disease depend on the patient\u2019s ...
di Meo, Nicola +5 more
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Common Neurologic Features of Lyme Disease That May Present to a Rheumatologist
Pathogens, 2023 Lyme disease, caused by Borrelia burgdorferi (Bb) infection, has a broad spectrum of clinical manifestations and severity. Patients with possible Lyme disease may seek out or be referred to rheumatologists.
Swati Govil +5 more
doaj +1 more source
The Heterogeneity, Distribution, and Environmental Associations of Borrelia burgdorferi Sensu Lato, the Agent of Lyme Borreliosis, in Scotland [PDF]
, 2014 Genospecies controls were obtained from the laboratory of Dr. Muriel Cornet at the Institut Pasteur, Paris. We thank Bob Furness for collecting ticks from passerine birds, Steph Vollmer for processing the samples from one site, E. Packer, A.
Bowman, Alan S +3 more
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Infection and ImmunityCurrently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells +6 more
doaj +1 more source
The impact of Pandemic COVID-19 on cases of Borreliosis infection in 2020
Journal of Education, Health and Sport, 2021 Borreliosis (Lyme borreliosis; Lyme disease) is a zoonotic disease caused by spirochetes from the genus Borrelia. In humans, the accidental host of ticks, the infection is transmitted by the bite of the tick - the spirochetes are present in the salivary
Karolina Rogulska +2 more
doaj +1 more source
Spirochetal Lipoproteins and Immune Evasion. [PDF]
, 2017 Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani +2 more
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Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]
, 2008 Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Aguero-Rosenfeld ME +57 more
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