Results 31 to 40 of about 86,084 (267)

Lyme Disease Pathogenesis [PDF]

Current Issues in Molecular Biology, 2021
Lyme disease Borrelia are obligately parasitic, tick- transmitted, invasive, persistent bacterial pathogens that cause disease in humans and non-reservoir vertebrates primarily through the induction of inflammation. During transmission from the infected tick, the bacteria undergo significant changes in gene expression, resulting in adaptation to the ...
Garcia, Brandon, Coburn, Jenifer, Hu, Linden T., Jewett, Mollie W., Kraiczy, Peter, Norris, Steven J., Skare, Jon   +6 more
openaire   +3 more sources

The multiplexed single-tier InBios Lyme Detect Multiplex ELISA is more sensitive than standard two-tier tests in the early stages of Lyme disease

Journal of Clinical Microbiology
There are nearly 500,000 cases of Lyme disease each year in the United States; 10%–20% of them result in the development of a debilitating chronic disease known as post-treatment Lyme disease.
Anna F. Hickman, Allison F. Weber, Elizabeth J. Horn, Peter J. Gwynne   +3 more
doaj   +1 more source

Spirochetal Lipoproteins and Immune Evasion. [PDF]

, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani, Christodoulides, Alexei, Kelesidis, Theodoros   +2 more
core   +1 more source

Therapy of lyme disease [PDF]

, 2016
Borrelia burgdorferi is highly susceptible to antibiotic treatment and the majority of patients profit from this treatment. Antibiotic selection, dose and route of administration, and duration of therapy for Lyme disease depend on the patient\u2019s ...
di Meo, Nicola, Errichetti, Enzo, Nan, Katiuscia, Pinzani, Caterina, Stinco, Giuseppe, Trevisan, Giusto   +5 more
core   +1 more source

Differentiating Peromyscus leucopus bone marrow-derived macrophages for characterization of responses to Borrelia burgdorferi and lipopolysaccharide

Infection and Immunity
Currently, most tools utilized in host-pathogen interaction studies depend on the use of human or mouse (Mus musculus) cells and tissues. While these species have led to countless breakthroughs in our understanding of infectious disease, there are ...
Christopher C. Wells, Tanja Petnicki-Ocwieja, Shumin Tan, Stephen C. Bunnell, Sam R. Telford, Linden T. Hu, Jeffrey S. Bourgeois   +6 more
doaj   +1 more source

Common Neurologic Features of Lyme Disease That May Present to a Rheumatologist

Pathogens, 2023
Lyme disease, caused by Borrelia burgdorferi (Bb) infection, has a broad spectrum of clinical manifestations and severity. Patients with possible Lyme disease may seek out or be referred to rheumatologists.
Swati Govil, Eugenio Capitle, Alexandra Lacqua, Reena Khianey, P.K. Coyle, Steven E. Schutzer   +5 more
doaj   +1 more source

Immunoblot analysis of the seroreactivity to recombinant Borrelia burgdorferi sensu lato antigens, including VlsE, in the long-term course of treated patients with Erythema migrans [PDF]

, 2008
Objective: We evaluated whether immunoblotting is capable of substantiating the posttreatment clinical assessment of patients with erythema migrans ( EM), the hallmark of early Lyme borreliosis.
Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Aguero-Rosenfeld ME, Bacon RM, Bettina Wilske, Bono JL, Bruckbauer HR, Christina Ambros-Rudolph, Coleman JL, Dressler F, Engstrom SM, Feder, Fung BP, Glatz M, Goettner G, Grodzicki RL, Guo BP, Hansen K, Hauser U, Helmut Kerl, Hofmann H, Hulshof MM, Jauris-Heipke S, Kalish RA, Lahdenne P, Lebech AM, Ledue TB, Liang FT, Liang FT, Magnarelli LA, Magnarelli LA, Marangoni A, Martin Glatz, Massarotti EM, Mullegger RR, Peltomaa M, Philipp MT, Picken MM, Plorer A, Rasiah C, Robert R. Müllegger, Roessler D, Ruzic-Sabljic E, Ryffel K, Shadick NA, Sillanpaa H, Simpson WJ, Smith RP, Stanek G, Stanek G, Volker Fingerle, Volkman DJ, Wilske B, Wilske B, Wilske B, Wilske B, Wormser GP, Zhang JR   +57 more
core   +1 more source

Lyme disease.

Nihon Naika Gakkai Zasshi, 1994
Lyme disease is a tick-borne disease, and recognized as a complex, multisystem disorder. An outbreak [correction of outback] of Lyme disease was first described in the United States in the 1970s. The presence of Borrelia burgdorferi, its causative agent, in the skin results in the development of characteristic expanding red skin lesions, erythema ...
  +18 more sources

The impact of Pandemic COVID-19 on cases of Borreliosis infection in 2020

Journal of Education, Health and Sport, 2021
Borreliosis (Lyme borreliosis; Lyme disease) is a zoonotic disease caused by spirochetes from the genus Borrelia. In humans, the accidental host of ticks, the infection is transmitted by the bite of the tick - the spirochetes are present in the salivary
Karolina Rogulska, Patrycja Piątek, Konrad Grzeszczak   +2 more
doaj   +1 more source

Lyme Disease Biobank: 10 years of 3 month follow-up visits from 2014 to 2023

Frontiers in Medicine
IntroductionLyme Disease Biobank (LDB) enrolls participants with signs and symptoms of early Lyme disease (LD) from endemic areas and makes samples available to researchers developing more accurate diagnostics. From 2014 to 23, 466 cases and 367 controls
Elizabeth J. Horn, George Dempsey, Anna M. Schotthoefer, Matthew McArdle, Allison F. Weber, Cathy De Luca, Bobbi S. Pritt, Elizabeth L. Maloney   +7 more
doaj   +1 more source