Results 91 to 100 of about 2,128,818 (392)

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Correlation between Lymph Node Ratio and Clinicopathological Features and Prognosis of IIIa-N2 Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2019
Background and objective IIIa-N2 non-small cell lung cancer was significant different in survival, although N stage of lung cancer based on anatomic location of metastasis lymph node.
Shanyuan ZHANG, Liang WANG, Fangliang LU, Yuquan PEI, Yue YANG   +4 more
doaj   +1 more source

Relationship of the number and size of superficial groin lymph nodes with the stage of secondary lymphatic edema [PDF]

, 2016
PURPOSE: This study evaluated the relationships of the size and number of superficial groin lymph nodes with the lower limb lymphedema stage and thus examined the role of superficial lymphatic lymph nodes in secondary lymphedema development.
Hiramatsu, Yuji, Kimata, Yoshihiro, Onoda, Satoshi, Seki, Noriko, Yamada, Kiyoshi   +4 more
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

The influence of tumor invasion in anastomotic line on survival of patient with gastric stump cancer [PDF]

, 2008
RACIONAL: O câncer do coto gástrico desenvolve- se no remanescente gástrico de gastrectomia realizada há pelo menos 5 anos por doença benigna e os sítios mais comuns de acometimento são próximo à anastomose e na pequena curvatura. Considera-se que o coto
BRESCIANI, Cláudio José Caldas, CARRASCO, Ana Lúcia Granja Scarabel Nogueira, CECCONELLO, Ivan, PEREZ, Rodrigo Oliva, ZILBERSTEIN, Bruno   +4 more
core   +2 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

The clinical value of Delphian and pre-tracheal lymph nodes in predicting lateral lymph nodes metastasis of papillary thyroid carcinoma

Annals of Medicine
Background Occult lymph node metastasis of papillary thyroid carcinoma is common. However, whether undergoing prophylactic lateral lymph node dissections is still controversial. This cross-sectional study with large cohort of patients aims to investigate
Chun Huang, Jing Zhou, Yuchen Zhuang, Tao Xu, Xinliang Su   +4 more
doaj   +1 more source

Efficacy of Methylene Blue in Sentinel Lymph Node Biopsy for Early Breast Cancer

European Journal of Breast Health, 2014
Objective:Sentinel lymph node biopsy is the recommended approach in the evaluation of axilla during breast cancer surgery. In this study, results of patients who underwent methylene blue sentinel lymph node biopsy were evaluated.Materials and Methods:The
Altan Özdemir, Burhan Mayir, Kenan Demirbakan, Nezihi Oygür   +3 more
doaj   +1 more source

Targeting Lymph Node Sinus Macrophages to Inhibit Lymph Node Metastasis

Molecular Therapy: Nucleic Acids, 2019
Lymph nodes are important peripheral immune organs in which numerous important immune responses occur. During the process of lymphatic metastasis, lymph nodes are also sites through which tumor cells must pass.
Junqing Hu, Jinhao Xu, Mingyue Li, Yanping Zhang, Huaiqiang Yi, Jiangning Chen, Lei Dong, Junfeng Zhang, Zhen Huang   +8 more
doaj   +1 more source

Surgical treatment of gastric cancer with special reference to lymph node removal [PDF]

, 1977
Factors influencing the prognosis in gastric cancer treated by curative resection include lymph node metastasis and the extent of invasion of the gastric wall. Lymph node metastasis can be removed surgically, but the extent of invasion is not amenable to
Okajima, Kunio
core   +1 more source