Results 101 to 110 of about 770,345 (334)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Integrative molecular profiling identifies two molecularly and clinically distinct subtypes of blastic plasmacytoid dendritic cell neoplasm

Blood Cancer Journal, 2022
Axel Künstner, Julian Schwarting, Hanno M. Witte, Veronica Bernard, Stephanie Stölting, Kathrin Kusch, Kumar Nagarathinam, Nikolas von Bubnoff, Eva Maria Murga Penas, Hartmut Merz, Hauke Busch, Alfred C. Feller, Niklas Gebauer   +12 more
doaj   +1 more source

A B-cell–associated gene signature classification of diffuse large B-cell lymphoma by NanoString technology

Blood Advances, 2018
: Gene expression profiling (GEP) by microarrays of diffuse large B-cell lymphoma (DLBCL) has enabled the categorization of DLBCL into activated B-cell–like and germinal center B-cell–like subclasses.
Thomas Yssing Michaelsen, Julia Richter, Rasmus Froberg Brøndum, Wolfram Klapper, Hans Erik Johnsen, Mads Albertsen, Karen Dybkær, Martin Bøgsted   +7 more
doaj  

Detection of Sentinel Lymph Nodes in Patients with Papillary Thyroid Cancer

Asian Journal of Surgery, 2003
To determine the feasibility of sentinel lymph node biopsy as a means of evaluating the cervical lymph nodes of patients with papillary thyroid cancer.
Hiroshi Takami, Yoshifumi Ikeda, Gengo Tajima   +2 more
doaj   +1 more source

Does preoperative axillary staging lead to overtreatment of women with screen detected breast cancer? [PDF]

, 2013
Aim To determine the impact of pre-operative axillary ultrasound staging in a screen detected breast cancer population Materials and Method Ultrasound and needle biopsy staging results alongside reference standard sentinel lymph node biopsy and ...
Kilburn-Toppin, F., Taylor-Phillips, Sian, Wallis, M. G.   +2 more
core   +4 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Difficulty of predicting lymph node metastasis on CT in patients with rectal neuroendocrine tumors.

PLoS ONE, 2019
BACKGROUND:Surgical indications for rectal neuroendocrine tumors with potential lymph node metastasis remain controversial. Although accurate preoperative diagnosis of nodal status may be helpful for treatment strategy, scant data about clinical values ...
Hajime Ushigome, Yosuke Fukunaga, Toshiya Nagasaki, Takashi Akiyoshi, Tsuyoshi Konishi, Yoshiya Fujimoto, Satoshi Nagayama, Masashi Ueno   +7 more
doaj   +1 more source

Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells. [PDF]

, 2009
The cellular dynamics of the egress of lymphocytes from lymph nodes are poorly defined. Here we visualized the branched organization of lymph node cortical sinuses and found that after entry, some T cells were retained, whereas others returned to the ...
Cyster, Jason G, Grigorova, Irina L, Okada, Takaharu, Pham, Trung HM, Phan, Tri Giang, Schwab, Susan R   +5 more
core  

Pathological Features of Breast Cancer seen in Northwestern Tanzania: A Nine Years Retrospective Study. [PDF]

, 2011
Breast cancer is more common in Western Countries compared to African populations. However in African population, it appears that the disease tends to be more aggressive and occurring at a relatively young age at the time of presentation. The aim of this
A Dobi, A Fregene, A Gondos, A Stark, C Maureen, CR Barkley, CW Elston, CW Elston, CY Mimi, D Huo, DE Henson, DM Parkin, DM Parkin, EJ Rafael, FA William, G Zavagno, H Amir, H Amir, H Amir, Kahima J Jackson, M Galukande, Mange M Manyama, MK Sheikh, O Ikpatt, O Ikpatt, OF Ikpatt, P Chatzidaki, P Robbins, Peter F Rambau, Philipo L Chalya, RD Leek, RL Bowen, T Hanagiri, T Hasebe   +33 more
core   +3 more sources

The resistance of a lymph node to lymph flow

Journal of British Surgery, 1984
Abstract The relationship between lymph flow, lymph node arterial and venous perfusion pressure and lymph node resistance have been studied in an in vivo isolated canine iliac lymph node perfused through an afferent lymphatic with heparinized canine plasma.
D Sizeland, Norman Browse, R L Doig
openaire   +4 more sources