Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Detection of Sentinel Lymph Nodes in Patients with Papillary Thyroid Cancer
Asian Journal of Surgery, 2003 To determine the feasibility of sentinel lymph node biopsy as a means of evaluating the cervical lymph nodes of patients with papillary thyroid cancer.
Hiroshi Takami +2 more
doaj +1 more source
Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells. [PDF]
, 2009 The cellular dynamics of the egress of lymphocytes from lymph nodes are poorly defined. Here we visualized the branched organization of lymph node cortical sinuses and found that after entry, some T cells were retained, whereas others returned to the ...
Cyster, Jason G +5 more
core
Action mechanism in vitro of sensitized regional lymph node cells on target cell. I. Anti-growth effect of regional lymph node cells of Ehrlich cancer transplanted mouse and that of normal lymph node cells induced by PHA, on Ehrlich cancer cell line (JTC-11) [PDF]
, 1971 Under in vivo conditions JTC-II cells derived from Ehrlich ascites tumor are led to destruction by lymph node cells by two processes. The one is the interaction of lymph node cells of the C57BL (♀) mouse sensitized with Ehrlich ...
Konaga, Eiji
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Blood Advances, 2018 : Gene expression profiling (GEP) by microarrays of diffuse large B-cell lymphoma (DLBCL) has enabled the categorization of DLBCL into activated B-cell–like and germinal center B-cell–like subclasses.
Thomas Yssing Michaelsen +7 more
doaj
Comparison of machine learning methods for classifying mediastinal lymph node metastasis of non-small cell lung cancer from 18F-FDG PET/CT images [PDF]
, 2017 The present study shows that the performance of CNN is not significantly different from the best classical methods and human doctors for classifying mediastinal lymph node metastasis of NSCLC from PET/CT images. Because CNN does not need tumor segmentation or feature calculation, it is more convenient and more objective than the classical methods ...
arxiv +1 more source
One-stage versus two-stage lymph node dissection after investigation of sentinel lymph node in cutaneous melanoma: a comparison of complications, costs, hospitalization times, and operation times [PDF]
, 2018 The aim of the study was to evaluate whether complication rate, costs, operation times, and hospitalization times differed in two different patient groups: in group 1, frozen section analysis of the sentinel lymph node and lymph node dissection were ...
Haug, M., Pierer, G., von Känel, O.
core
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
World Journal of Surgical Oncology, 2012 Background Central and lateral lymph node metastases are quite common in patients with papillary thyroid carcinoma, and the predictors for those metastases have been well studied.
Kim Yong-Seok, Park Woo-Chan
doaj +1 more source