Results 141 to 150 of about 2,107,695 (393)

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption. [PDF]

, 2019
The role of lymphoid tissue as a potential source of HIV-1 rebound following interruption of antiretroviral therapy (ART) is uncertain. To address this issue, we compared the latent viruses obtained from CD4+ T cells in peripheral blood and lymph nodes ...
Ablanedo-Terrazas, Yuria, Barton, John P, Cohen, Yehuda Z, Damsgaard, Tine, Del Rio Estrada, Perla M, Denton, Paul W, Garcia Noceda, Marco, Lorenzi, Julio CC, Lu, Ching-Lan, Nussenzweig, Michel C, Oliveira, Thiago Y, Pai, Joy A, Reyes-Teran, Gustavo, Søgaard, Ole S, Tolstrup, Martin, Vibholm, Line K   +15 more
core   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

t(11;14)-positive mantle cell lymphomas lacking cyclin D1 (CCND1) immunostaining because of a CCND1 mutation or exclusive expression of the CCND1b isoform

Haematologica, 2018
Ingram Iaccarino, Lamis Afify, Sietse M. Aukema, Katharina Reddemann, Philipp Schütt, Martin Flür, Wolfram Klapper   +6 more
doaj   +1 more source

Clinical Study on Prelaryngeal Lymph Node Metastasis in Papillary Thyroid Carcinoma

Cancer Management and Research, 2020
Jin-Xing Gong,1 Jian-Wei Gu,1 Feng Ji,1 Kun Li,1 Qi Zhu,1 Fang-Ying Gu,1 Yan Chen,1 Qing-Hai Ji2 1Department Four of Surgery, Kunshan Hospital of Traditional Chinese Medicine, Kunshan 215300, People’s Republic of China; 2Head & Neck Surgery ...
Gong JX, Gu JW, Ji F, Li K, Zhu Q, Gu FY, Chen Y, Ji QH   +7 more
doaj  

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Abdominopelvic lymph-node dissection in cancer of the rectum and distal colon [PDF]

, 1951
Michael R. Deddish
openalex   +1 more source

Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer

Journal of the American Medical Association (JAMA), 2017
Babak Ehteshami Bejnordi, M. Veta, Paul Johannes van Diest, B. van Ginneken, N. Karssemeijer, G. Litjens, Jeroen A. W. M. van der Laak, M. Hermsen, Quirine F. Manson, M. Balkenhol, Oscar G. F. Geessink, N. Stathonikos, M. V. van Dijk, P. Bult, F. Beca, Andrew H. Beck, Dayong Wang, A. Khosla, Rishab Gargeya, H. Irshad, Aoxiao Zhong, Q. Dou, Quanzheng Li, Hao Chen, Huangjing Lin, P. Heng, C. Hass, Elia Bruni, Q. Wong, U. Halici, Mustafa Ümit Öner, R. Cetin-Atalay, Matt Berseth, V. Khvatkov, A. Vylegzhanin, Oren Z. Kraus, M. Shaban, N. Rajpoot, Ruqayya Awan, K. Sirinukunwattana, Talha Qaiser, Y. Tsang, David Tellez, Jonas Annuscheit, P. Hufnagl, Mira Valkonen, K. Kartasalo, Leena Latonen, P. Ruusuvuori, Kaisa Liimatainen, Shadi Albarqouni, Bharti Mungal, A. George, S. Demirci, N. Navab, Seiryo Watanabe, S. Seno, Y. Takenaka, H. Matsuda, Hady Ahmady Phoulady, V. Kovalev, A. Kalinovsky, V. Liauchuk, G. Bueno, M. Fernández-Carrobles, I. Serrano, O. Deniz, Daniel Racoceanu, Rui Venâncio   +68 more
semanticscholar   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source